{"id":"W1538988309","doi":"10.3109/21691401.2015.1047557","title":"Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions?","year":2015,"lang":"en","type":"review","venue":"Artificial Cells Nanomedicine and Biotechnology","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Medical Research Council; Canadian Institutes of Health Research; Canadian Blood Services","keywords":"Medicine; Blood transfusion; Red blood cell; Hemorrhagic shock; Shock (circulatory); Surgery; Intensive care medicine; Anesthesia; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001716618,0.0004116473,0.0009052119,0.0004193728,0.0003717315,0.001933731,0.0006967979,0.003677616,0.0094456],"category_scores_gemma":[0.003211606,0.0002222858,0.0005474318,0.0002975749,0.001509205,0.003911891,0.0007681875,0.003306072,0.004525884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007418558,"about_ca_system_score_gemma":0.0007996728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006807143,"about_ca_topic_score_gemma":0.0009940573,"domain_scores_codex":[0.9992303,0.0001864952,0.00005390493,0.0001424593,0.0002870838,0.00009978864],"domain_scores_gemma":[0.9987745,0.000601839,0.000138903,0.00004733902,0.0003308424,0.0001064888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005514473,0.0003144525,0.0009842153,0.01035887,0.0001535688,0.0009328896,0.0003228426,0.0004217481,0.01803372,0.05789951,0.2786216,0.6314051],"study_design_scores_gemma":[0.00005456179,0.0003130787,0.0005053509,0.001305126,0.0000594807,0.001553226,0.000260891,0.0002680902,0.005440581,0.0157007,0.9744918,0.00004708264],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00448524,0.8556094,0.005593618,0.1032832,0.01512436,0.00008675081,0.0002468879,0.0002047823,0.01536564],"genre_scores_gemma":[0.05499729,0.7970518,0.00685263,0.08972208,0.01617358,0.0002573803,0.0004084889,0.0001427302,0.03439396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0094456,"threshold_uncertainty_score":0.03159869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02045605373505165,"score_gpt":0.2646714551700907,"score_spread":0.2442154014350391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}