{"id":"W1539736798","doi":"10.1034/j.1399-0004.2003.00143.x","title":"Genetic epidemiology of alpha‐1 antitrypsin deficiency in North America and Australia/New Zealand: Australia, Canada, New Zealand and the United States of America","year":2003,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Alpha Foundation for the Improvement of Mine Safety and Health; Alpha-1 Foundation","keywords":"Epidemiology; Disease; Medicine; Allele; Genetic epidemiology; Demography; Environmental health; Biology; Genetics; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003174744,0.0001701249,0.0008728104,0.0001176018,0.00002415884,0.000003619184,0.00009015419,0.0001094612,0.0001206321],"category_scores_gemma":[0.0009545539,0.0001198999,0.00009995066,0.0005840406,0.0009121079,0.000009712648,0.00003372767,0.0002624637,0.00000219729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001597731,"about_ca_system_score_gemma":0.0003435122,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.3650703,"about_ca_topic_score_gemma":0.1579669,"domain_scores_codex":[0.9976024,0.0004336947,0.001191205,0.0003042095,0.0001652325,0.0003032716],"domain_scores_gemma":[0.9978031,0.001047215,0.0003969567,0.0003032015,0.00008573525,0.0003638291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001128164,0.00009360674,0.9824579,0.00002912294,0.00005583244,0.000013479,0.0001612412,0.000646921,0.00003612787,0.00001272979,0.01475167,0.001628603],"study_design_scores_gemma":[0.003219721,0.0004580801,0.9768364,0.00007980283,0.0002140194,0.0000204292,0.0001588257,0.0007629492,0.00006846703,0.0003543982,0.01769044,0.0001364387],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972767,0.0007763627,0.0001654224,0.001515514,0.00002949625,0.0001758883,0.00003970658,0.00000446645,0.00001646665],"genre_scores_gemma":[0.9871469,0.003705659,0.004390906,0.001535082,0.00004476085,0.000001771842,0.00005909305,0.00001123786,0.003104574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2071034,"threshold_uncertainty_score":0.857398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07670463388786421,"score_gpt":0.3688543969687006,"score_spread":0.2921497630808365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}