{"id":"W1540300413","doi":"10.1186/ar1959","title":"Autoimmune targeting of key components of RNA interference","year":2006,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Arthritis Society; National Institutes of Health; University of Calgary","keywords":"Rheumatology; Key (lock); RNA interference; Medicine; Computational biology; RNA; Internal medicine; Bioinformatics; Computer science; Biology; Genetics; Computer security; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005211337,0.0001029414,0.0001883287,0.00009572478,0.00006438479,0.00001486241,0.0003524457,0.00008662933,0.0001021034],"category_scores_gemma":[0.00004784027,0.000097383,0.0000939594,0.0001378715,0.0002765378,0.000007047486,0.000129091,0.0001381876,0.00001363898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007462272,"about_ca_system_score_gemma":0.00005394305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000991992,"about_ca_topic_score_gemma":0.00006523391,"domain_scores_codex":[0.9986479,0.0001828714,0.0003446972,0.0002376498,0.0002824662,0.0003043748],"domain_scores_gemma":[0.9991218,0.00003095132,0.00008694235,0.000318481,0.0004057992,0.00003603172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000207708,0.0001433841,0.002315764,0.000008772276,0.00003133293,0.000003060215,0.00007956183,0.00001546799,0.9663926,0.0001218901,0.002405806,0.02827469],"study_design_scores_gemma":[0.0007568226,0.0009578121,0.009448233,0.0001019436,6.914906e-7,0.00000309846,0.0001062742,0.00004682986,0.9777148,0.0004671036,0.01029361,0.0001027641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865474,0.01102104,0.0001943217,0.00007605366,0.00006500019,0.0001521293,0.00002220529,0.000005606648,0.001916261],"genre_scores_gemma":[0.9901066,0.008978571,0.0003007625,0.00002162804,0.00008681302,0.00001491958,0.0001030626,0.00001451429,0.0003730981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02817193,"threshold_uncertainty_score":0.3971163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.036280688363582,"score_gpt":0.3136685908779884,"score_spread":0.2773879025144064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}