{"id":"W1540300413","doi":"10.1186/ar1959","title":"Autoimmune targeting of key components of RNA interference","year":2006,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Arthritis Society; National Institutes of Health; University of Calgary","keywords":"Rheumatology; Key (lock); RNA interference; Medicine; Computational biology; RNA; Internal medicine; Bioinformatics; Computer science; Biology; Genetics; Computer security; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002735466,0.0005825518,0.0003039942,0.0003757929,0.0002171791,0.0002865545,0.0001937487,0.0003263169,0.001735425],"category_scores_gemma":[0.0002754944,0.0001160635,0.0002398455,0.0001273515,0.0002613408,0.0001591923,0.0003414352,0.0004243064,0.0005498391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003509459,"about_ca_system_score_gemma":0.0002075512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001876061,"about_ca_topic_score_gemma":0.0002281155,"domain_scores_codex":[0.9996604,0.00005750269,0.00002823228,0.00007709937,0.0001092209,0.00006751858],"domain_scores_gemma":[0.9998245,0.00003467937,0.00005559895,0.00002410022,0.00002633763,0.00003493324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003554762,0.000011772,0.0003768765,0.0000309907,0.000006826737,0.00009601152,0.000009797584,0.00001987214,0.9961747,0.0002386977,0.0000691458,0.002929915],"study_design_scores_gemma":[0.000009244871,0.0002618151,0.004953643,0.000007977516,0.00002097054,0.001261128,0.00001489804,0.0005252716,0.9878923,0.0001537518,0.004894975,0.000004037291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562873,0.01288915,0.0220929,0.0003135327,0.0001286744,0.00008336288,0.000249433,0.0004861942,0.007469452],"genre_scores_gemma":[0.9914075,0.001849293,0.003126845,0.00009176681,0.00003009878,0.00002512313,0.0002408675,0.00001834608,0.003210089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001735425,"threshold_uncertainty_score":0.005805552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.036280688363582,"score_gpt":0.3136685908779884,"score_spread":0.2773879025144064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}