{"id":"W1542202136","doi":"10.1111/j.1471-4159.2005.03200.x","title":"The excitoprotective effect of <i>N</i>‐methyl‐<scp>d</scp>‐aspartate receptors is mediated by a brain‐derived neurotrophic factor autocrine loop in cultured hippocampal neurons","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Excitotoxicity; Neuroprotection; Tropomyosin receptor kinase B; NMDA receptor; Glutamate receptor; Neurotrophic factors; Neurotrophin; Brain-derived neurotrophic factor; Ifenprodil; Chemistry; Hippocampal formation; Biology; Pharmacology; Receptor; Cell biology; Neuroscience; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009491607,0.0005019492,0.0003733421,0.0001150489,0.0001047894,0.0002567928,0.0002190637,0.0001957128,0.001242154],"category_scores_gemma":[0.0001588363,0.0001485617,0.0002708872,0.0001136233,0.0002260161,0.0002469236,0.0001629875,0.000451342,0.0003812714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002497168,"about_ca_system_score_gemma":0.0002800155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001639491,"about_ca_topic_score_gemma":0.002557448,"domain_scores_codex":[0.9999303,0.00000776068,0.00001058463,0.00001087485,0.00001768911,0.00002282923],"domain_scores_gemma":[0.999895,0.00001484967,0.00003358375,0.00001215772,0.00001879277,0.00002553551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001446779,0.00001237498,0.00008601323,0.0000451754,0.000005889783,0.00005034396,0.00001148503,0.00001972637,0.9985271,0.00002143298,0.00002394541,0.00105203],"study_design_scores_gemma":[0.00003622713,0.0006222685,0.004340667,0.00001299977,0.0000392759,0.0002852804,0.00003143541,0.0004016609,0.993411,0.00004638583,0.0007675844,0.000005085615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929889,0.003353636,0.001629772,0.0001180329,0.00003461958,0.00001701036,0.0002277066,0.0001155789,0.001514773],"genre_scores_gemma":[0.9945781,0.002078724,0.001238454,0.00005778881,0.00001554143,0.00002770475,0.0003568093,0.00002228535,0.001624589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001639491,"threshold_uncertainty_score":0.004155457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171107988182505,"score_gpt":0.259801028496643,"score_spread":0.248089948614818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}