{"id":"W1542253046","doi":"10.3389/fmicb.2015.00755","title":"Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold","year":2015,"lang":"en","type":"review","venue":"Frontiers in Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Guelph; Carleton University; National Research Council Canada","funders":"National Research Council Canada","keywords":"Bioconjugation; Filamentous bacteriophage; Bacteriophage; Immunogenicity; Biology; Phage display; Phagemid; Computational biology; Nanotechnology; Immune system; Genetics; Antibody; Escherichia coli; Materials science; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002398549,0.0003779787,0.0009472228,0.0001351469,0.000125516,0.00002615611,0.0005169255,0.0004214876,0.0004970267],"category_scores_gemma":[0.00001132414,0.0002606197,0.0002282089,0.0003955803,0.0004510476,0.0001081856,0.0003082992,0.0003542478,0.00006434824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003579232,"about_ca_system_score_gemma":0.00008353941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001332505,"about_ca_topic_score_gemma":0.00007208459,"domain_scores_codex":[0.99822,0.0002346377,0.0006154748,0.0005579529,0.00005379791,0.0003181675],"domain_scores_gemma":[0.9989282,0.00006059915,0.0005016713,0.0004196928,0.00001747127,0.00007231336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006188569,0.0004218418,0.000652618,0.001247638,0.0003798699,0.00000872554,0.0003784733,0.000003629038,0.1418642,0.0001400379,0.02681906,0.828022],"study_design_scores_gemma":[0.000335621,0.0001134415,0.0007776915,0.000342633,0.0002367771,0.0002119105,0.00004615994,0.000004184728,0.0002002306,0.0004189724,0.9970244,0.0002879622],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006326965,0.9857866,0.0004469633,0.00008651803,0.001536791,0.002658426,0.002247416,0.00002292265,0.0008874119],"genre_scores_gemma":[0.005730545,0.989221,0.001190757,0.0003138887,0.0001384794,0.0005320945,0.001426731,0.00005475565,0.0013918],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9702054,"threshold_uncertainty_score":0.9999846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01460299956900612,"score_gpt":0.2610344029450907,"score_spread":0.2464314033760846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}