{"id":"W1543799147","doi":"10.1093/pch/16.8.e61","title":"From genes to vaccine: A breakthrough in the prevention of meningococcal group B disease","year":2011,"lang":"en","type":"article","venue":"Paediatrics & Child Health","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Novartis (Canada)","funders":"","keywords":"Meningococcal disease; Reverse vaccinology; Outbreak; Vaccination; Meningococcal vaccine; Disease; Medicine; Virology; Meningitis; Neisseria meningitidis; Antigen; Microbiology; Biology; Immunology; Immunization; Pediatrics; Bacteria; Genetics; Epitope; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001873633,0.0007230214,0.0008824348,0.0008570126,0.0002715981,0.001864556,0.0005190574,0.002800332,0.005873493],"category_scores_gemma":[0.002431835,0.0002954496,0.000513435,0.0006653075,0.001725274,0.002651817,0.0008428684,0.003834654,0.002037995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001070432,"about_ca_system_score_gemma":0.001154693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007840583,"about_ca_topic_score_gemma":0.001032972,"domain_scores_codex":[0.9995595,0.0001287326,0.00002852609,0.0000629358,0.0001256067,0.00009480384],"domain_scores_gemma":[0.9990726,0.0003869873,0.0001010063,0.00004349494,0.0001481326,0.0002477987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001035863,0.000765618,0.001790702,0.002369658,0.0001318865,0.0006681929,0.0003433009,0.001322875,0.03509697,0.04039405,0.09360492,0.8224759],"study_design_scores_gemma":[0.0006593202,0.001937142,0.003798112,0.001305193,0.0001258342,0.001705833,0.0002941203,0.0009931437,0.01340177,0.03483341,0.9408885,0.00005764214],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.027749,0.8055223,0.009626387,0.1366643,0.00795475,0.00007233791,0.0003211116,0.0002974666,0.01179243],"genre_scores_gemma":[0.1191851,0.7902706,0.01641419,0.05053527,0.007482545,0.00009029614,0.0004091417,0.0001375644,0.01547536],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005873493,"threshold_uncertainty_score":0.01964879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036580460609432,"score_gpt":0.2727823967748406,"score_spread":0.2524165921687462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}