{"id":"W1543857745","doi":"10.3389/fimmu.2015.00247","title":"Adoptive T Cell Therapy Targeting CD1 and MR1","year":2015,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; National Institutes of Health; University of Toronto; Canadian Institutes of Health Research; Government of Ontario","keywords":"T cell; CD1; Adoptive cell transfer; Antigen; Immunotherapy; Immunology; Effector; Human leukocyte antigen; Biology; Cancer research; Cell biology; Medicine; Antigen-presenting cell; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008492442,0.0004834925,0.00269637,0.0007980093,0.00005191883,0.00002209757,0.0003238858,0.0008611763,0.0005049582],"category_scores_gemma":[0.00008858136,0.0003940735,0.0002716917,0.000504637,0.000442156,0.00005237948,0.0001887743,0.00164355,0.00005198593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005749467,"about_ca_system_score_gemma":0.0007308909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000527408,"about_ca_topic_score_gemma":0.000001408766,"domain_scores_codex":[0.9972519,0.0005631447,0.0006191292,0.0006297188,0.0002576985,0.0006783732],"domain_scores_gemma":[0.9988199,0.0001159374,0.0002367945,0.0005707357,0.0001298817,0.0001267371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002722878,0.0001014606,0.0001435832,0.001405573,0.0004432647,0.0001255901,0.0003672336,6.536784e-8,0.0000574989,0.000008007672,0.01947915,0.9775963],"study_design_scores_gemma":[0.001965109,0.0005434284,0.00001506339,0.001228351,0.0001315595,0.0001102707,0.0003978267,0.000005319416,0.00002025438,0.00009122927,0.9951865,0.0003050969],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009869781,0.9906601,0.00007038732,0.00005165514,0.001393896,0.00153838,0.00001548211,0.00004798471,0.006123432],"genre_scores_gemma":[0.000003702518,0.9856356,0.00328935,0.00005465228,0.0002327928,0.0001546664,0.0001953633,0.0001175992,0.01031629],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9772912,"threshold_uncertainty_score":0.9998511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04836614119864218,"score_gpt":0.3427829699181532,"score_spread":0.294416828719511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}