{"id":"W1543857745","doi":"10.3389/fimmu.2015.00247","title":"Adoptive T Cell Therapy Targeting CD1 and MR1","year":2015,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; National Institutes of Health; University of Toronto; Canadian Institutes of Health Research; Government of Ontario","keywords":"T cell; CD1; Adoptive cell transfer; Antigen; Immunotherapy; Immunology; Effector; Human leukocyte antigen; Biology; Cancer research; Cell biology; Medicine; Antigen-presenting cell; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002449039,0.0004696686,0.0006395251,0.0009682582,0.0001467289,0.0004854477,0.000390845,0.0006351483,0.002771391],"category_scores_gemma":[0.0001805268,0.0001226845,0.0002600964,0.0007245427,0.0002252554,0.0005721434,0.0003686485,0.0009514926,0.002034151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002908477,"about_ca_system_score_gemma":0.0004106467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003555026,"about_ca_topic_score_gemma":0.000605428,"domain_scores_codex":[0.9999235,0.00001066629,0.000007441035,0.00001589901,0.00003125365,0.00001135252],"domain_scores_gemma":[0.9999446,0.00001882071,0.000009294537,0.000001904114,0.00001687907,0.000008424284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008479798,0.000102115,0.0001753973,0.008446175,0.0000381904,0.0002234099,0.00004518023,0.0002447331,0.01283722,0.004073083,0.02011648,0.9536132],"study_design_scores_gemma":[0.00001858331,0.0001719031,0.000572336,0.0009054288,0.0000588887,0.001640492,0.00003933671,0.0001014573,0.003886851,0.001237658,0.9913546,0.00001246461],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007375489,0.99455,0.0006450921,0.0003233482,0.0002610184,0.00001397013,0.00003102667,0.00002348287,0.003414504],"genre_scores_gemma":[0.00318587,0.9931749,0.000515066,0.0002692778,0.0001624217,0.00001864805,0.00006222066,0.00000295218,0.002608676],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002771391,"threshold_uncertainty_score":0.009271204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04836614119864218,"score_gpt":0.3427829699181532,"score_spread":0.294416828719511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}