{"id":"W1544147210","doi":"10.1111/j.1365-2958.2010.07216.x","title":"Better late than early: delayed translation of intron‐encoded endonuclease I‐TevI is required for efficient splicing of its host group I intron","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Intron; Biology; RNA splicing; Group II intron; Homing endonuclease; Endonuclease; Genetics; Group I catalytic intron; Gene; Cell biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003213089,0.0002327018,0.0003488627,0.00008953553,0.00005324007,0.000008233019,0.0002748349,0.0004070379,0.00003720028],"category_scores_gemma":[0.0000536857,0.0002244261,0.0002483202,0.00007854716,0.0001243558,0.000004011546,0.00007238441,0.0001171569,0.000005561669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007437341,"about_ca_system_score_gemma":0.00003250378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002631715,"about_ca_topic_score_gemma":0.00002042793,"domain_scores_codex":[0.9985572,0.000123336,0.0004555289,0.0004598459,0.00005990344,0.0003442471],"domain_scores_gemma":[0.9990551,0.0000308197,0.0002766838,0.0004425339,0.0001326042,0.00006218326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000478818,0.00007937518,0.00005351229,0.00006751516,0.0001236981,0.000001776383,0.0001467242,0.00003281869,0.9966637,0.000193019,0.00003455655,0.002124452],"study_design_scores_gemma":[0.001097562,0.0007515636,0.00006935597,0.00002603783,0.00007685717,0.00001214524,0.000009890976,0.0001802005,0.9946749,0.0000669228,0.002815439,0.0002191746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9616674,0.0005098729,0.03637207,0.0002609293,0.0002132519,0.0007088942,0.0002032587,0.00001070222,0.00005359439],"genre_scores_gemma":[0.9916567,0.00003268765,0.007606687,0.0002669269,0.00007475739,0.0000490719,0.0002359359,0.000044421,0.00003282741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02998926,"threshold_uncertainty_score":0.9151829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007118429649636909,"score_gpt":0.2211097850694351,"score_spread":0.2139913554197982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}