{"id":"W1544147210","doi":"10.1111/j.1365-2958.2010.07216.x","title":"Better late than early: delayed translation of intron‐encoded endonuclease I‐TevI is required for efficient splicing of its host group I intron","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Intron; Biology; RNA splicing; Group II intron; Homing endonuclease; Endonuclease; Genetics; Group I catalytic intron; Gene; Cell biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000250928,0.000523895,0.000334335,0.0001686867,0.0001626731,0.0006736132,0.000415199,0.000397404,0.0013717],"category_scores_gemma":[0.0002931327,0.0002376271,0.0002599553,0.0001100229,0.0003813317,0.0003666002,0.0003575703,0.0009490313,0.0008204374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005122042,"about_ca_system_score_gemma":0.0003828077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003136673,"about_ca_topic_score_gemma":0.000473104,"domain_scores_codex":[0.9996868,0.00003023268,0.00004089541,0.0001018168,0.0000879658,0.00005233277],"domain_scores_gemma":[0.9995645,0.00007884929,0.000140373,0.00007330299,0.00003770861,0.0001053165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002354251,0.000007702214,0.00007289859,0.000006265834,7.45006e-7,0.00001371434,0.00000281458,0.00001183717,0.9995779,0.00004448129,0.000005360939,0.0002326649],"study_design_scores_gemma":[0.000004828442,0.00006742698,0.001255579,0.000001639498,0.000003861501,0.0001241908,0.000005621383,0.0003696447,0.9975551,0.00002708675,0.0005827194,0.000002338615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989281,0.0008875001,0.008151066,0.0001196423,0.00006674112,0.00002247274,0.000279113,0.000199862,0.0009926325],"genre_scores_gemma":[0.9923729,0.0002273454,0.003877917,0.00006000407,0.00001580139,0.00002095559,0.0006294093,0.0001308103,0.002664671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013717,"threshold_uncertainty_score":0.004588842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007118429649636909,"score_gpt":0.2211097850694351,"score_spread":0.2139913554197982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}