{"id":"W1544678760","doi":"10.1111/j.1462-5822.2010.01470.x","title":"The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling","year":2010,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Biology; Effector; Enteropathogenic Escherichia coli; Type three secretion system; Secretion; Virulence; Phosphorylation; Microbiology; Cell biology; Immunoprecipitation; Cell culture; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007169865,0.0002560357,0.0001044815,0.0001517049,0.0001549375,0.0002934442,0.000107801,0.0002255197,0.0009907882],"category_scores_gemma":[0.0000855206,0.0001014834,0.0001646445,0.00008842316,0.0001571137,0.0002061345,0.0002343978,0.0003057713,0.0003540841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001954565,"about_ca_system_score_gemma":0.00008174982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001863968,"about_ca_topic_score_gemma":0.0002686452,"domain_scores_codex":[0.9999328,0.00001279106,0.000003660518,0.00001101155,0.00001884876,0.00002093256],"domain_scores_gemma":[0.9999585,0.000007740882,0.000009638581,0.00000503174,0.000006316262,0.00001268253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001249847,0.00001876067,0.0004362174,0.00001376809,0.000002208745,0.00007485985,0.00000658301,0.00003381688,0.9984109,0.0000691126,0.00001749231,0.0007912724],"study_design_scores_gemma":[0.00002975289,0.0001823312,0.02227282,0.000004597741,0.000008833773,0.0005635279,0.00005647861,0.001851592,0.9735281,0.00007374789,0.00142442,0.0000037245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982857,0.0002843829,0.0008344704,0.0000380524,0.000003448681,0.000003085187,0.00003365125,0.00001205509,0.000505066],"genre_scores_gemma":[0.9980045,0.0002188161,0.0007444462,0.00001645163,0.000003243151,0.000004993834,0.0001119033,0.00000340335,0.0008923115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009907882,"threshold_uncertainty_score":0.003314495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005567716198553985,"score_gpt":0.2170929365438896,"score_spread":0.2115252203453356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}