{"id":"W1544678760","doi":"10.1111/j.1462-5822.2010.01470.x","title":"The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling","year":2010,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Biology; Effector; Enteropathogenic Escherichia coli; Type three secretion system; Secretion; Virulence; Phosphorylation; Microbiology; Cell biology; Immunoprecipitation; Cell culture; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004304538,0.0002611018,0.0002350049,0.00003134004,0.000335327,0.00005913079,0.0003064207,0.0002127201,0.00001622059],"category_scores_gemma":[0.000186078,0.0001698395,0.00006184675,0.0001013668,0.0006525397,0.000004609786,0.0003593698,0.0003946708,0.00003235452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001042497,"about_ca_system_score_gemma":0.0001148189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002477875,"about_ca_topic_score_gemma":0.0002707989,"domain_scores_codex":[0.9985237,0.0002012816,0.0001984951,0.0004978898,0.00005746261,0.0005211947],"domain_scores_gemma":[0.9990529,0.0001773278,0.00009116027,0.0003676602,0.0002067973,0.0001041442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003416259,0.00004369436,0.001513152,0.00003701189,0.0000952095,0.00001123485,0.0001170884,0.000001316831,0.9974214,0.00001413225,0.0002932263,0.0001108685],"study_design_scores_gemma":[0.0007398358,0.0009526642,0.0009441673,0.00001117259,0.00002460926,0.00003182631,0.0001537253,0.00002043984,0.9441233,0.000004768873,0.05273848,0.0002550317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943554,0.004257402,0.0001161852,0.0001326895,0.0003223873,0.0005135635,0.00004539248,0.0000171017,0.0002398398],"genre_scores_gemma":[0.9974687,0.0004724164,0.0003137119,0.0000843746,0.0001487756,0.00004968311,0.0001359016,0.00003162715,0.001294788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05329816,"threshold_uncertainty_score":0.6925856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005567716198553985,"score_gpt":0.2170929365438896,"score_spread":0.2115252203453356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}