{"id":"W1545043714","doi":"","title":"Yeast two-hybrid analysis of a human trabecular meshwork cDNA library identified EFEMP2 as a novel PITX2 interacting protein.","year":2012,"lang":"en","type":"article","venue":"PubMed","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Two-hybrid screening; cDNA library; Biology; Trabecular meshwork; Homeobox; Transcription factor; Complementary DNA; PITX2; Immunoprecipitation; PDZ domain; Myocilin; Cell biology; Genetics; Molecular biology; Gene; Glaucoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002001289,0.0007915583,0.0006444385,0.0004277307,0.0002700463,0.0003554247,0.0003386703,0.0003956923,0.002505435],"category_scores_gemma":[0.0002124086,0.0002110158,0.0007337427,0.0006243325,0.0001792842,0.0001482908,0.0003062542,0.0006885552,0.00160959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004322102,"about_ca_system_score_gemma":0.0002573701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001431613,"about_ca_topic_score_gemma":0.001727484,"domain_scores_codex":[0.9998398,0.00001610521,0.00001248225,0.00004847374,0.00005424516,0.00002887769],"domain_scores_gemma":[0.9999081,0.00003780812,0.00001208156,0.000006937268,0.00001675073,0.00001829692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001212524,0.0000424203,0.0004432241,0.00005507639,0.00001790437,0.0002719772,0.0000184773,0.00007894017,0.9971926,0.00007683551,0.0002022754,0.001478937],"study_design_scores_gemma":[0.0001047091,0.0005047768,0.03009282,0.00002889783,0.0001427345,0.00349344,0.0001119393,0.006836642,0.9427034,0.0001823176,0.01576493,0.00003340588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9422349,0.002542227,0.03228107,0.0007046651,0.0001588085,0.0003004101,0.01559102,0.0005631486,0.00562368],"genre_scores_gemma":[0.8457996,0.002756176,0.04940552,0.0005922902,0.00005802051,0.00037534,0.08455244,0.0002649644,0.01619576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002505435,"threshold_uncertainty_score":0.008381486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01385478376622096,"score_gpt":0.2455849051269553,"score_spread":0.2317301213607344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}