{"id":"W1545043714","doi":"","title":"Yeast two-hybrid analysis of a human trabecular meshwork cDNA library identified EFEMP2 as a novel PITX2 interacting protein.","year":2012,"lang":"en","type":"article","venue":"PubMed","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Two-hybrid screening; cDNA library; Biology; Trabecular meshwork; Homeobox; Transcription factor; Complementary DNA; PITX2; Immunoprecipitation; PDZ domain; Myocilin; Cell biology; Genetics; Molecular biology; Gene; Glaucoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002942314,0.0001436689,0.0002137548,0.0001458377,0.00007437776,0.00002047292,0.0001606776,0.00009565162,0.0000792697],"category_scores_gemma":[0.00005806527,0.0001380135,0.0001825111,0.0002866038,0.00006185002,0.00002320382,0.0001284773,0.0000728603,0.000006539039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001128784,"about_ca_system_score_gemma":0.00002120515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001581041,"about_ca_topic_score_gemma":0.00001145494,"domain_scores_codex":[0.9989518,0.00006623347,0.0002896701,0.0002641785,0.0001044864,0.0003236227],"domain_scores_gemma":[0.9994263,0.000006931901,0.0001829148,0.0002481911,0.00002689567,0.0001087639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001391314,0.000228071,0.04877134,0.00002470661,0.001734063,0.000001762689,0.0001235146,0.00002845575,0.9296244,0.000214801,0.0002063104,0.01890341],"study_design_scores_gemma":[0.0003509154,0.00002083055,0.3155978,0.000008516591,0.0002059481,0.000007765431,0.00004455632,0.0000112068,0.6812531,0.0000399532,0.00229152,0.0001678988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957755,0.0003582964,0.0002915126,0.00004924813,0.0001335875,0.0004146521,0.00002322522,0.00001671448,0.002937272],"genre_scores_gemma":[0.9961944,0.000005500824,0.0003030659,0.00009212775,0.0001529307,0.0003140638,0.0007414873,0.00001734086,0.002179063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2668265,"threshold_uncertainty_score":0.5628027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01385478376622096,"score_gpt":0.2455849051269553,"score_spread":0.2317301213607344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}