{"id":"W1545275730","doi":"10.1038/emboj.2011.54","title":"TGF‐β signalling is mediated by two autonomously functioning TβRI:TβRII pairs","year":2011,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Cancer Institute; University of Texas Health Science Center at San Antonio; National Institutes of Health","keywords":"Biology; Signalling; Signal transduction; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005233731,0.0001890875,0.0001423423,0.00004144866,0.0004362397,0.00007414607,0.000422927,0.00008225589,0.0009216884],"category_scores_gemma":[0.0001043905,0.0001400953,0.0001898295,0.00008145792,0.0001034852,0.000009824929,0.00008278118,0.0002891269,0.00008228915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002573232,"about_ca_system_score_gemma":0.0001641467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000232311,"about_ca_topic_score_gemma":0.000006150174,"domain_scores_codex":[0.9987357,0.000140858,0.000327857,0.000231148,0.0002170757,0.0003473212],"domain_scores_gemma":[0.9991798,0.00003472955,0.0002208761,0.0002636811,0.0001168738,0.0001840136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004551573,0.0002530605,0.005447261,0.00001550076,0.000801241,0.00004410579,0.002198222,0.000573963,0.902827,0.00003872144,0.08218798,0.005157841],"study_design_scores_gemma":[0.002775886,0.000748094,0.002305454,0.0001072661,0.0003572929,0.0005855244,0.001356709,0.0008942842,0.8866386,0.001049578,0.1022713,0.0009099075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873825,0.003242986,0.006312699,0.0002018642,0.0004228231,0.00009306992,0.00001603099,0.00003883998,0.002289215],"genre_scores_gemma":[0.9968773,0.00008201565,0.0005225358,0.0008231543,0.0006846865,0.000007700011,0.00003395716,0.00003949489,0.0009291917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02008337,"threshold_uncertainty_score":0.9999916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01936049348437953,"score_gpt":0.2353519828216564,"score_spread":0.2159914893372768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}