{"id":"W1545474158","doi":"10.3233/jad-130539","title":"Glial Activation in AβPP/PS1 Mice is Associated with Infiltration of IFNγ-Producing Cells","year":2013,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Science Foundation Ireland; Strategic Innovation Fund; Health Research Board","keywords":"Astrogliosis; Astrocytosis; Microglia; Proinflammatory cytokine; Pathogenesis; Long-term potentiation; Gliosis; Senile plaques; Genetically modified mouse; Presenilin; Pathology; Biology; Neuroscience; Infiltration (HVAC); Immunology; Alzheimer's disease; Inflammation; Medicine; Transgene; Disease; Central nervous system; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002046067,0.0001294761,0.0001954082,0.0002533034,0.00005981203,0.00006250328,0.0001459634,0.00003771725,0.0002009295],"category_scores_gemma":[0.0005093418,0.0001086955,0.00007253492,0.0003773585,0.00003700696,0.001023474,0.0000165487,0.0001853033,0.00001888952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000247908,"about_ca_system_score_gemma":0.0001482484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000101619,"about_ca_topic_score_gemma":0.000001928018,"domain_scores_codex":[0.9983118,0.0002132397,0.0005878321,0.0002054966,0.0005317023,0.0001499873],"domain_scores_gemma":[0.9984844,0.0001167331,0.0008152612,0.0001590707,0.0002634471,0.0001611351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001298672,0.0001630017,0.0003221895,0.000005377962,0.0000126475,0.00001331104,0.0002834024,0.001050938,0.997083,0.0001074455,0.0005567802,0.0002720042],"study_design_scores_gemma":[0.0008231093,0.0001586331,0.01445562,0.00006390864,0.00006397277,0.000004906934,0.00002501657,0.001585492,0.9824169,0.000271335,0.0000231629,0.0001079334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980301,0.00001710981,0.0003254928,0.001027902,0.0002254849,0.0002810608,0.000006689436,0.00001446957,0.00007172301],"genre_scores_gemma":[0.9986269,0.00001486773,0.0001668602,0.00103493,0.00008929939,0.000005507149,0.000002049924,0.00001754345,0.00004205798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01466613,"threshold_uncertainty_score":0.4432474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03364107783067225,"score_gpt":0.2497145975286395,"score_spread":0.2160735196979672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}