{"id":"W1545507338","doi":"10.1111/j.1476-5381.2010.00953.x","title":"Participation of nuclear factor (erythroid 2‐related), factor 2 in ameliorating lithocholic acid‐induced cholestatic liver injury in mice","year":2010,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; University of Toronto","keywords":"Lithocholic acid; Liver injury; Glutathione; GCLC; Oxidative stress; Cytoprotection; Pharmacology; Biology; Bile acid; Alkaline phosphatase; Alanine transaminase; Biochemistry; Endocrinology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002623021,0.0008317406,0.0005159033,0.0006130551,0.0002266798,0.0003091979,0.0002749313,0.000585119,0.001678529],"category_scores_gemma":[0.0001380013,0.0002609051,0.0003799439,0.0001937979,0.0004258791,0.0003859788,0.0001986771,0.0007969186,0.0003771003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002818733,"about_ca_system_score_gemma":0.0002964569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000344246,"about_ca_topic_score_gemma":0.0005726702,"domain_scores_codex":[0.9998223,0.00003337856,0.00002338508,0.00004384961,0.00003488759,0.00004224995],"domain_scores_gemma":[0.9998127,0.000009505127,0.00006408302,0.00001913902,0.00002166228,0.00007295806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001573224,0.0002288481,0.0004089772,0.00009708095,0.00001467373,0.00007236633,0.00001754869,0.00004588461,0.9960901,0.00008444728,0.0000604848,0.001306266],"study_design_scores_gemma":[0.0003103748,0.003068089,0.006002136,0.00002538498,0.0001052828,0.0004992625,0.00006274148,0.0006333077,0.9863651,0.0001191802,0.002797387,0.00001167536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917623,0.002784583,0.003278465,0.0003034772,0.00008244044,0.00009909906,0.0006073808,0.0002451154,0.000837115],"genre_scores_gemma":[0.9847247,0.002338115,0.004832127,0.0002373334,0.0000419376,0.0002887181,0.00108329,0.00006336008,0.006390339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001678529,"threshold_uncertainty_score":0.005615234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01372924688212158,"score_gpt":0.3002675085899184,"score_spread":0.2865382617077968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}