{"id":"W1546762202","doi":"10.1002/9780470054581.eib012","title":"Affinity Fusions: Gene Expression","year":2009,"lang":"en","type":"other","venue":"Encyclopedia of Industrial Biotechnology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Genome Canada","keywords":"Computational biology; Proteome; Recombinant DNA; Fusion protein; Affinity chromatography; Proteomics; Folding (DSP implementation); Protein tag; Biochemistry; Biology; Chemistry; Computer science; Gene; Engineering; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001824715,0.0003947272,0.000994135,0.0009485575,0.00005311937,0.000004838397,0.0004113601,0.003578566,0.005058112],"category_scores_gemma":[0.0005611985,0.0003079652,0.0002284285,0.0004832888,0.000418537,0.00001750822,0.0002782976,0.001635656,0.0002546342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004646483,"about_ca_system_score_gemma":0.0003933566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003958993,"about_ca_topic_score_gemma":0.0000333785,"domain_scores_codex":[0.9978692,0.00008121983,0.0005293529,0.0005351657,0.0004982008,0.0004868429],"domain_scores_gemma":[0.998583,0.00008941245,0.0003560009,0.0007243446,0.0000552832,0.0001919442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003945002,0.0003103162,0.0005537644,0.00006354626,0.0001001513,0.0001727929,0.00001274929,1.01562e-7,0.01728301,0.0003993641,0.8824555,0.09825426],"study_design_scores_gemma":[0.001297882,0.0007544764,0.00006880868,0.0006424169,0.0000711906,0.00006205301,0.00001859448,7.126705e-7,0.06507748,0.0001424212,0.9316112,0.0002528047],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.007848534,0.00425877,0.00002489095,0.005793462,0.0009573642,0.001193866,0.00028354,0.0005110559,0.9791285],"genre_scores_gemma":[0.0008997314,0.03767656,0.00639232,0.0002168352,0.003614694,0.00003709989,0.0004024827,0.0003319017,0.9504284],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.09800145,"threshold_uncertainty_score":0.9999372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03461080417862258,"score_gpt":0.2974470611381216,"score_spread":0.262836256959499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}