{"id":"W1546762202","doi":"10.1002/9780470054581.eib012","title":"Affinity Fusions: Gene Expression","year":2009,"lang":"en","type":"other","venue":"Encyclopedia of Industrial Biotechnology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Genome Canada","keywords":"Computational biology; Proteome; Recombinant DNA; Fusion protein; Affinity chromatography; Proteomics; Folding (DSP implementation); Protein tag; Biochemistry; Biology; Chemistry; Computer science; Gene; Engineering; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006376302,0.0009696892,0.0006057327,0.0008032959,0.0004201939,0.001401265,0.0009568681,0.0009465877,0.00851274],"category_scores_gemma":[0.0005003997,0.0004026727,0.0006815848,0.001494792,0.0004894265,0.0006086166,0.001123154,0.001542326,0.01881832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00089373,"about_ca_system_score_gemma":0.0005095481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008305692,"about_ca_topic_score_gemma":0.0008176667,"domain_scores_codex":[0.9991692,0.000109914,0.00007086325,0.0001670916,0.0003493197,0.0001335173],"domain_scores_gemma":[0.9997806,0.00004390598,0.00003505024,0.00004396905,0.00005923062,0.0000372679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002245815,0.0001191987,0.0002511832,0.0004836875,0.00003270089,0.0002512743,0.00008016287,0.0003670939,0.9451389,0.006488241,0.01105701,0.03550594],"study_design_scores_gemma":[0.00003944308,0.0001198004,0.0007933366,0.00007002145,0.00005449424,0.0008134666,0.00003954176,0.001899195,0.7457877,0.001461248,0.2488889,0.00003269553],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"other","genre_scores_codex":[0.1875688,0.03017483,0.6277909,0.004536645,0.002981657,0.001809106,0.02730058,0.0120225,0.1058151],"genre_scores_gemma":[0.4983472,0.02487146,0.204938,0.001859353,0.0004351017,0.001341685,0.05786677,0.001698044,0.2086424],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.00851274,"threshold_uncertainty_score":0.02847791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03461080417862258,"score_gpt":0.2974470611381216,"score_spread":0.262836256959499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}