{"id":"W1546936681","doi":"10.1038/onc.2015.136","title":"Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Izaak Walton Killam Health Centre; Toronto Western Hospital; Dalhousie University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Golgi apparatus; Biology; Oncolytic virus; Cell biology; Apoptosis; Programmed cell death; Intracellular; Transfection; Virus; Cell culture; Virology; Endoplasmic reticulum; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002121279,0.0004715727,0.0002565102,0.0004309137,0.0002049629,0.0004505949,0.0002445672,0.0003569938,0.001265786],"category_scores_gemma":[0.0001584932,0.0001976547,0.0004347689,0.0001620384,0.0002842859,0.0003610868,0.0002112449,0.0009014532,0.0004779037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007019232,"about_ca_system_score_gemma":0.0003039484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007486719,"about_ca_topic_score_gemma":0.0009717057,"domain_scores_codex":[0.9998165,0.00002590608,0.00001303413,0.00003473944,0.00004701573,0.00006291088],"domain_scores_gemma":[0.999836,0.00005511033,0.00002832938,0.00003288648,0.00001952589,0.00002814492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002195839,0.00003196766,0.00009917547,0.00001590803,0.000007244883,0.00004277159,0.00001696576,0.00007941161,0.9979256,0.0003884785,0.000039603,0.001133228],"study_design_scores_gemma":[0.00001327333,0.00009989931,0.0005221982,0.000001682511,0.000008003099,0.00009067985,0.00001094466,0.0005270193,0.9979078,0.00006406042,0.0007524234,0.000001983999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875179,0.001668414,0.007546219,0.0001430566,0.00005898053,0.00004589564,0.0003292165,0.0002041757,0.002486125],"genre_scores_gemma":[0.9941051,0.0003908854,0.002215932,0.00002797327,0.00001034397,0.00002141272,0.0002862824,0.00003913391,0.002902971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001265786,"threshold_uncertainty_score":0.0050928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02830797628263373,"score_gpt":0.306502975345484,"score_spread":0.2781949990628503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}