{"id":"W1547093349","doi":"10.1016/j.devcel.2015.06.005","title":"Nuclear β-Catenin under Control","year":2015,"lang":"en","type":"letter","venue":"Developmental Cell","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Health Canada","keywords":"Biology; Demethylation; Wnt signaling pathway; Cell biology; Nucleus; Catenin; Lysine; Ubiquitin; Cell nucleus; Transcription factor; Nuclear protein; Transcription (linguistics); Genetics; Gene; Signal transduction; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009808792,0.0003100201,0.0002203377,0.00006509007,0.00006239676,0.00003563537,0.0002399342,0.001012775,0.0001778876],"category_scores_gemma":[0.00000667529,0.0003283066,0.00010261,0.00006911402,0.00006337438,0.000002719685,0.0001098487,0.0004347725,0.0005515185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002134592,"about_ca_system_score_gemma":0.0003654873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001743026,"about_ca_topic_score_gemma":0.000009306003,"domain_scores_codex":[0.998572,0.00005418026,0.0002543874,0.0004979739,0.000282079,0.0003393944],"domain_scores_gemma":[0.9994659,0.000005414486,0.0001389331,0.0002248752,0.00009175023,0.00007306796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000357604,0.00001203102,0.00002278668,0.00002350013,0.00008016304,0.00001414802,0.0000234955,0.00005099418,0.0646255,8.980061e-7,0.9347794,0.0003313383],"study_design_scores_gemma":[0.0009378878,0.00006358387,0.00009346996,0.0000139884,0.00003650422,0.00004261989,0.00002503243,0.00001581923,0.02546989,0.00003038231,0.9728286,0.0004422796],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2522042,0.009099898,0.002044123,0.5816576,0.008663068,0.004010616,0.0008565355,0.0004381286,0.1410258],"genre_scores_gemma":[0.2577816,0.000182428,0.002132338,0.6586072,0.006655982,0.00007082095,0.01110306,0.0004050873,0.06306145],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.07796432,"threshold_uncertainty_score":0.9999169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009714911532618335,"score_gpt":0.2023090502257293,"score_spread":0.192594138693111,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}