{"id":"W1547804365","doi":"10.1071/rdv16n1ab26","title":"26 ABERRANT REPROGRAMMING OF IMPRINTED GENE EXPRESSION IN ENLARGED PLACENTAS OF MICE CLONED FROM ES CELLS TREATED WITH TSA OR 5AZAC","year":2004,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep de Saint Hyacinthe; Université de Montréal; University of Guelph","funders":"International Council for Canadian Studies; Natural Sciences and Engineering Research Council of Canada; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Genomic imprinting; Biology; DNA methylation; Reprogramming; Epigenetics; Molecular biology; XIST; Gene; Gene expression; Somatic cell nuclear transfer; Histone; Housekeeping gene; Andrology; Genetics; X-inactivation; Blastocyst; X chromosome; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031845,0.0001440371,0.0002285473,0.00004986359,0.00004804836,0.000007689197,0.00006789319,0.00009428612,0.00001206206],"category_scores_gemma":[0.00007208543,0.0001120074,0.00002827355,0.0001185751,0.00006373739,0.000006000101,0.00008670965,0.00006017878,7.219568e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002619462,"about_ca_system_score_gemma":0.0001172112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003316672,"about_ca_topic_score_gemma":0.0001001296,"domain_scores_codex":[0.9985861,0.00004803484,0.000449698,0.0006149706,0.0001322053,0.000169047],"domain_scores_gemma":[0.9993005,0.000007921983,0.0001728199,0.0003719442,0.0000961496,0.00005062205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007765665,0.0002219403,0.02811166,0.00006184856,0.00004428947,0.000001365418,0.0005405984,0.0001287391,0.9631313,2.147655e-7,0.000001651477,0.006979791],"study_design_scores_gemma":[0.001018346,0.000135965,0.2711936,0.0000785865,0.000007927431,0.000007378911,0.0003280635,0.00000372612,0.7268735,0.000005147432,0.0002489552,0.00009878859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971353,0.0005227486,0.001955039,0.00003128412,0.00005509814,0.0002765283,0.000004617141,0.00001250502,0.00000691043],"genre_scores_gemma":[0.9644708,0.0001038558,0.03529401,0.000005993205,0.00001395631,0.00001681589,0.0000423449,0.00001242674,0.00003978107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.243082,"threshold_uncertainty_score":0.4567529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01444423078156517,"score_gpt":0.2303122800972771,"score_spread":0.215868049315712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}