{"id":"W1547804365","doi":"10.1071/rdv16n1ab26","title":"26 ABERRANT REPROGRAMMING OF IMPRINTED GENE EXPRESSION IN ENLARGED PLACENTAS OF MICE CLONED FROM ES CELLS TREATED WITH TSA OR 5AZAC","year":2004,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep de Saint Hyacinthe; Université de Montréal; University of Guelph","funders":"International Council for Canadian Studies; Natural Sciences and Engineering Research Council of Canada; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Genomic imprinting; Biology; DNA methylation; Reprogramming; Epigenetics; Molecular biology; XIST; Gene; Gene expression; Somatic cell nuclear transfer; Histone; Housekeeping gene; Andrology; Genetics; X-inactivation; Blastocyst; X chromosome; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001868713,0.0003179616,0.0003134819,0.0003810027,0.00009754048,0.0003063021,0.0002424581,0.0002169998,0.00197483],"category_scores_gemma":[0.0001494225,0.0002123558,0.0003327825,0.0001582279,0.0003287312,0.0001569116,0.0002477369,0.0005953356,0.0004104778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185736,"about_ca_system_score_gemma":0.0001644063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006452685,"about_ca_topic_score_gemma":0.0005250754,"domain_scores_codex":[0.9997482,0.00003522361,0.000025163,0.00007061083,0.00007746479,0.00004341612],"domain_scores_gemma":[0.9997732,0.00005084328,0.0000649439,0.0000331062,0.00001947893,0.0000584151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002468838,0.000003331368,0.00007029645,0.000007673279,0.000002260279,0.00003436126,0.0000112684,0.000009566031,0.9996023,0.00001908254,0.000004129685,0.0002111028],"study_design_scores_gemma":[0.000008567757,0.0001804518,0.008284498,0.00000521331,0.00001771972,0.0002265476,0.00004426811,0.0003613118,0.9894829,0.00003045586,0.001354877,0.00000303133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936203,0.0008736506,0.00338651,0.00006207891,0.00003360115,0.00002146667,0.0005349013,0.0000811407,0.00138632],"genre_scores_gemma":[0.9900419,0.0009470149,0.002541125,0.00006421604,0.0000127645,0.00005505978,0.001128164,0.00007213966,0.005137653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00197483,"threshold_uncertainty_score":0.00660646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01444423078156517,"score_gpt":0.2303122800972771,"score_spread":0.215868049315712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}