{"id":"W1549061267","doi":"10.1073/pnas.1505317112","title":"Identification of divergent type VI secretion effectors using a conserved chaperone domain","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":174,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canada Research Chairs; Canada Foundation for Innovation","keywords":"Effector; Type VI secretion system; Chaperone (clinical); Secretion; Biology; Computational biology; Cell biology; Genetics; Biochemistry; Virulence; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001208724,0.00005197472,0.00008611486,0.00005920041,0.00007189886,0.000007929514,0.000296444,0.00004980648,0.000002275279],"category_scores_gemma":[0.0008428406,0.0000364166,0.00003567637,0.0002909008,0.0005640198,0.00001837959,0.0001848974,0.00003684648,3.473931e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002049223,"about_ca_system_score_gemma":0.0000498637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007222605,"about_ca_topic_score_gemma":9.608058e-8,"domain_scores_codex":[0.9989814,0.00001288248,0.0002053327,0.0001411771,0.0005754629,0.00008376167],"domain_scores_gemma":[0.99913,0.00001419985,0.0002996305,0.000008329285,0.0005222163,0.00002567948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004617359,0.00002027961,0.008458481,0.00003751209,0.00001703945,9.22931e-10,0.0000795325,0.00003906732,0.9903886,0.0007236895,0.0001728917,0.00001672223],"study_design_scores_gemma":[0.0001828447,0.00009840445,0.04072973,0.00003244467,0.000005795801,0.000001434191,0.0001466976,0.0003666142,0.9563696,0.001949413,0.00007820704,0.00003884505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991177,0.0001148008,0.000004852048,0.0003317714,0.00002177434,0.0002282311,0.000009071964,0.000001716904,0.0001700344],"genre_scores_gemma":[0.9994686,0.00002366312,0.0004071242,0.0000185224,0.00004161296,0.000008402815,5.252917e-7,0.000002190163,0.00002941052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03401904,"threshold_uncertainty_score":0.2078154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0704807296939244,"score_gpt":0.3440876735044192,"score_spread":0.2736069438104948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}