{"id":"W1549179575","doi":"10.1111/j.1365-2567.2009.03160.x","title":"HHQ and PQS, two <i>Pseudomonas aeruginosa</i> quorum‐sensing molecules, down‐regulate the innate immune responses through the nuclear factor‐κB pathway","year":2009,"lang":"en","type":"article","venue":"Immunology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Ministry of Education and Human Resources Development","keywords":"Innate immune system; Pseudomonas aeruginosa; Immune system; Mutant; Tumor necrosis factor alpha; Microbiology; Biology; Quorum sensing; Cell culture; Immunology; Cell biology; Virulence; Gene; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001443548,0.0003411085,0.0002215492,0.000119325,0.00008158978,0.0001800556,0.000189014,0.0002480328,0.001178772],"category_scores_gemma":[0.00009669209,0.0001045853,0.000269658,0.00008078208,0.0002878787,0.0001654756,0.0001591136,0.0003906543,0.000238221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002013448,"about_ca_system_score_gemma":0.0002160763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006998166,"about_ca_topic_score_gemma":0.0008431134,"domain_scores_codex":[0.9998128,0.00003719613,0.00002124826,0.00002523581,0.00005779858,0.00004581498],"domain_scores_gemma":[0.9998872,0.00002187255,0.00003449136,0.00001368652,0.00001321465,0.00002950858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007416243,0.00001637795,0.0001073337,0.00001819968,0.00000208708,0.00002073792,0.000003785696,0.0000185363,0.9991923,0.00004758814,0.00001534989,0.0004834137],"study_design_scores_gemma":[0.00003392457,0.0005140657,0.00433693,0.000002758218,0.000005998428,0.0001357587,0.00001753901,0.0003383412,0.9934521,0.00003725508,0.001121908,0.000003465177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941276,0.001465339,0.002807204,0.00014657,0.00004207041,0.00004168608,0.0002923344,0.00006190941,0.001015242],"genre_scores_gemma":[0.9948968,0.0004992534,0.002519248,0.0001139054,0.00001435854,0.00004138117,0.0003915229,0.00001264089,0.001510898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001178772,"threshold_uncertainty_score":0.003943384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008394543856726711,"score_gpt":0.2385288745700992,"score_spread":0.2301343307133724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}