{"id":"W1549179575","doi":"10.1111/j.1365-2567.2009.03160.x","title":"HHQ and PQS, two <i>Pseudomonas aeruginosa</i> quorum‐sensing molecules, down‐regulate the innate immune responses through the nuclear factor‐κB pathway","year":2009,"lang":"en","type":"article","venue":"Immunology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Ministry of Education and Human Resources Development","keywords":"Innate immune system; Pseudomonas aeruginosa; Immune system; Mutant; Tumor necrosis factor alpha; Microbiology; Biology; Quorum sensing; Cell culture; Immunology; Cell biology; Virulence; Gene; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000262361,0.0003510212,0.0003105828,0.00003528787,0.0004765267,0.0001095764,0.0005755851,0.0002753468,0.00001778523],"category_scores_gemma":[0.0001686336,0.0002284983,0.0001337458,0.0001368866,0.000937235,0.00001271197,0.0003186279,0.0003267635,0.00002504196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002300106,"about_ca_system_score_gemma":0.00009265519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001133297,"about_ca_topic_score_gemma":0.00002829114,"domain_scores_codex":[0.9978509,0.0004835179,0.0004152508,0.0005355931,0.0001401207,0.0005746265],"domain_scores_gemma":[0.9984159,0.0000827925,0.0002299527,0.00113864,0.00009536951,0.0000373599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006189439,0.00003306069,0.0001841906,0.000003902474,0.0001340219,0.00002337467,0.0003692408,0.000007048115,0.9889148,0.001738194,0.0005426111,0.007430609],"study_design_scores_gemma":[0.002003686,0.0009284533,0.1119,0.00007807458,0.00007145217,0.0008328407,0.0008236654,0.00003899817,0.639025,0.00259281,0.2408881,0.0008169174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850106,0.008961322,0.0002422743,0.004056723,0.0003725972,0.0003165876,0.00002778839,0.00004235087,0.000969751],"genre_scores_gemma":[0.9946562,0.001916734,0.0007129975,0.001718576,0.0001667604,0.000002110737,0.00003712219,0.00004521639,0.0007442523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3498898,"threshold_uncertainty_score":0.9317889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008394543856726711,"score_gpt":0.2385288745700992,"score_spread":0.2301343307133724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}