{"id":"W1549484669","doi":"10.1111/j.1744-7917.2012.01562.x","title":"<i>In vitro</i> and <i>in vivo</i> application of RNA interference for targeting genes involved in peritrophic matrix synthesis in a lepidopteran system","year":2012,"lang":"en","type":"article","venue":"Insect Science","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Biology; Midgut; Chitin; Gene silencing; RNA interference; RNA silencing; RNA; Gene; Mucin 2; In vivo; Molecular biology; Gene expression; Cell biology; Biochemistry; Genetics; Botany; Larva","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009360467,0.0001188426,0.0001948882,0.0002117648,0.0000350775,0.00001609963,0.0002410969,0.00008435136,6.284708e-7],"category_scores_gemma":[0.0001074551,0.0001186376,0.0000286676,0.0004150531,0.000163403,0.00002448429,0.00007367936,0.00006504257,3.959035e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000629042,"about_ca_system_score_gemma":0.00007769751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003059046,"about_ca_topic_score_gemma":0.0008499531,"domain_scores_codex":[0.9987916,0.00005356457,0.0003417297,0.0003273415,0.0001125909,0.0003731404],"domain_scores_gemma":[0.9995769,0.00004255385,0.00009488464,0.0001936632,0.0000462991,0.00004571073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000164674,0.00004763309,0.03587222,0.0001385501,9.693345e-7,8.085233e-7,0.000233628,0.00008903872,0.9626451,0.00003966705,0.000003204649,0.0007645409],"study_design_scores_gemma":[0.0003203311,0.00004506416,0.006640224,0.00008446316,0.000002243899,0.000002654583,0.0003039648,0.002090018,0.9902015,0.00002088727,0.0001523878,0.0001362522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964594,0.00223451,0.0007558056,0.00003535284,0.00008465334,0.000326892,0.00001016673,0.0000030278,0.00009022046],"genre_scores_gemma":[0.9977834,0.0001553294,0.001791912,0.00004231508,0.00005358163,0.0001553944,0.000002284914,0.000008637553,0.000007168736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.029232,"threshold_uncertainty_score":0.4837902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006064625342689,"score_gpt":0.2510944734836741,"score_spread":0.2410338272302472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}