{"id":"W1549484669","doi":"10.1111/j.1744-7917.2012.01562.x","title":"<i>In vitro</i> and <i>in vivo</i> application of RNA interference for targeting genes involved in peritrophic matrix synthesis in a lepidopteran system","year":2012,"lang":"en","type":"article","venue":"Insect Science","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada","keywords":"Biology; Midgut; Chitin; Gene silencing; RNA interference; RNA silencing; RNA; Gene; Mucin 2; In vivo; Molecular biology; Gene expression; Cell biology; Biochemistry; Genetics; Botany; Larva","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002945584,0.0005050024,0.0002829606,0.0001745285,0.0002141487,0.0004777141,0.0002950139,0.0003754148,0.0008425143],"category_scores_gemma":[0.0001432667,0.0002465016,0.0004088764,0.0001024461,0.0003029055,0.0001943373,0.0001872092,0.0007449072,0.0005548603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004589619,"about_ca_system_score_gemma":0.0001960895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001412486,"about_ca_topic_score_gemma":0.001498463,"domain_scores_codex":[0.9996825,0.00006933293,0.00003649883,0.00008778975,0.00007546876,0.00004850236],"domain_scores_gemma":[0.9998584,0.00003467698,0.00005098114,0.00002199117,0.00001644999,0.00001741604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001594432,0.000006696528,0.00002937105,0.00002572786,0.000001740117,0.000008022005,0.000006143006,0.00002901414,0.9995825,0.00002555522,0.00001602266,0.0002531401],"study_design_scores_gemma":[0.0000094408,0.0002375625,0.001890354,0.000005351248,0.00001694607,0.0000900724,0.00001444418,0.0005597288,0.9954337,0.0000186113,0.001718205,0.000005500103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9645184,0.006950478,0.01819817,0.0002926483,0.0001498318,0.0001836942,0.001229353,0.0003472678,0.00813023],"genre_scores_gemma":[0.9608786,0.00429416,0.02365335,0.0003143681,0.00006448632,0.0003229167,0.002453222,0.0001092387,0.007909724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001412486,"threshold_uncertainty_score":0.003329992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006064625342689,"score_gpt":0.2510944734836741,"score_spread":0.2410338272302472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}