{"id":"W1549733180","doi":"10.1002/prot.24290","title":"Crystal structures of <i>Klebsiella pneumoniae</i> pantothenate kinase in complex with N‐substituted pantothenamides","year":2013,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Wellcome Trust","keywords":"Klebsiella pneumoniae; Microbiology; Klebsiella; Crystal (programming language); Biology; Escherichia coli; Biochemistry; Gene; Computer science; Programming language","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002479065,0.0005259196,0.0007553358,0.0002346791,0.0008921436,0.0007308094,0.001045537,0.0007420955,0.002267492],"category_scores_gemma":[0.0006556732,0.0004429931,0.0004224664,0.0005576533,0.0002652632,0.0003971196,0.0002946449,0.00144311,0.0003243777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001857888,"about_ca_system_score_gemma":0.001607014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02637114,"about_ca_topic_score_gemma":0.03665449,"domain_scores_codex":[0.9996568,0.00003931293,0.00001996048,0.00005648868,0.0001428272,0.00008456107],"domain_scores_gemma":[0.9996928,0.00006980084,0.00005377124,0.00001448559,0.00009030393,0.00007891434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003663261,0.00111361,0.02671253,0.001957317,0.000767048,0.003836905,0.002214679,0.02533234,0.8838195,0.004977419,0.02401835,0.02158715],"study_design_scores_gemma":[0.001943551,0.001164953,0.1374637,0.0002599476,0.0008087997,0.004607758,0.004157815,0.1843754,0.5754384,0.002366744,0.08695621,0.0004567923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892552,0.002254684,0.001335434,0.0006712746,0.00008247259,0.00002413195,0.00219121,0.0002914667,0.003894073],"genre_scores_gemma":[0.9749166,0.002189719,0.008264816,0.0002295805,0.00001820461,0.00005457693,0.01064682,0.0001686411,0.003510945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02637114,"threshold_uncertainty_score":0.05243522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718408198276305,"score_gpt":0.2104974791693321,"score_spread":0.193313397186569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}