{"id":"W1550040503","doi":"10.1111/j.1365-3083.2011.02578.x","title":"Differential Binding and Internalization of <i>Clostridium difficile</i> Toxin A by Human Peripheral Blood Monocytes, Neutrophils and Lymphocytes","year":2011,"lang":"en","type":"article","venue":"Scandinavian Journal of Immunology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Dr Hadwen Trust; Wellcome Trust","keywords":"Toxin; Trypan blue; Clostridium difficile toxin A; Peripheral blood mononuclear cell; Microbiology; Monocyte; Biology; Clostridium difficile; Alexa Fluor; Molecular biology; Immunology; Cell; In vitro; Fluorescence; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000195687,0.0001638389,0.000235416,0.0001223846,0.0002181384,0.0004012166,0.000098959,0.0003111556,0.001213842],"category_scores_gemma":[0.0002000154,0.0001459243,0.0001789665,0.0001361273,0.0001355593,0.0001678674,0.0002140722,0.0002196638,0.0004575442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001945937,"about_ca_system_score_gemma":0.0001477311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001199205,"about_ca_topic_score_gemma":0.001280847,"domain_scores_codex":[0.9997559,0.000061641,0.00001507067,0.00003840199,0.00004015182,0.00008885273],"domain_scores_gemma":[0.9998968,0.00003722019,0.00001779679,0.00001003887,0.00002248655,0.00001568095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004679902,0.00002029135,0.00224341,0.00005169633,0.000004813734,0.0001162574,0.0000999485,0.000034456,0.9950476,0.00005053419,0.00003746368,0.001825602],"study_design_scores_gemma":[0.00008853573,0.002716908,0.2038715,0.00007150962,0.00006733465,0.002171808,0.0008682905,0.001547441,0.7844865,0.000175205,0.003904804,0.00003003613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974547,0.001069783,0.0006586478,0.00002089881,0.000004510534,0.000008799127,0.00006730231,0.000005682574,0.0007096998],"genre_scores_gemma":[0.9964809,0.0007125423,0.001091471,0.00005408345,0.000009077055,0.0000261061,0.000233346,0.000004490777,0.001387944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001213842,"threshold_uncertainty_score":0.004060745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02077767088258695,"score_gpt":0.258785883587527,"score_spread":0.23800821270494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}