{"id":"W1550732900","doi":"10.1002/stem.1659","title":"Switch from Canonical to Noncanonical Wnt Signaling Mediates High Glucose-Induced Adipogenesis","year":2014,"lang":"en","type":"article","venue":"Stem Cells","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Lawson Health Research Institute; National Eye Institute; Michigan State University; National Institutes of Health; College of Engineering, Michigan State University; Canadian Diabetes Association; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Adipogenesis; Biology; Wnt signaling pathway; Progenitor cell; Mesenchymal stem cell; Cell biology; Stem cell; Bone marrow; Cellular differentiation; Multipotent Stem Cell; Endocrinology; Cancer research; Signal transduction; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007688802,0.0002237075,0.0001104453,0.0001182566,0.00009097036,0.0003287591,0.00008995667,0.00009276699,0.001217133],"category_scores_gemma":[0.00008173673,0.00009672299,0.000128686,0.0001056508,0.0001739726,0.000130372,0.0002177578,0.0002570444,0.0002179983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002239876,"about_ca_system_score_gemma":0.0001910546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004803178,"about_ca_topic_score_gemma":0.0009863179,"domain_scores_codex":[0.9999217,0.00001388774,0.000007238435,0.00001230142,0.00001735432,0.00002740098],"domain_scores_gemma":[0.9999584,0.000007805806,0.00001107723,0.000005133502,0.000003281405,0.00001419074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001910659,0.00002433778,0.0006656108,0.00004172311,0.000003776048,0.00009578014,0.00001207103,0.00006927008,0.996549,0.0004172601,0.00005039573,0.001879644],"study_design_scores_gemma":[0.00002304094,0.0001040963,0.008425151,0.000008366854,0.00001541477,0.0002189598,0.00003900908,0.001151892,0.9879918,0.000147964,0.001870581,0.000003724785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957139,0.0008794483,0.001528339,0.0000718011,0.00002234355,0.0000096437,0.0001461461,0.00003610118,0.001592321],"genre_scores_gemma":[0.9975336,0.0007317959,0.0007348236,0.00003032248,0.000005661525,0.000009563848,0.0001288234,0.000008990755,0.0008163723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001217133,"threshold_uncertainty_score":0.004071712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03151110654130702,"score_gpt":0.2865605144011594,"score_spread":0.2550494078598524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}