{"id":"W1551700340","doi":"10.1111/j.1476-5381.2012.02014.x","title":"Epithelium‐dependent modulation of responsiveness of airways from caveolin‐1 knockout mice is mediated through cyclooxygenase‐2 and 5‐lipoxygenase","year":2012,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Zileuton; Cyclooxygenase; Methacholine; Arachidonate 5-lipoxygenase; Endocrinology; Internal medicine; Arachidonic acid; Chemistry; Leukotriene; Eicosanoid; Lysophosphatidic acid; Rho kinase inhibitor; Receptor; Biology; Signal transduction; Medicine; Rho-associated protein kinase; Lung; Biochemistry; Enzyme; Respiratory disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004355325,0.0001476654,0.0003804069,0.00006708517,0.00004944865,0.000007219925,0.0001906462,0.0002044794,0.0001724621],"category_scores_gemma":[0.0001323471,0.0001659421,0.0001290199,0.00009142534,0.0001872151,0.00002887555,0.0001013721,0.0001721754,0.000002164456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001513439,"about_ca_system_score_gemma":0.0001506957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002358253,"about_ca_topic_score_gemma":0.00002790858,"domain_scores_codex":[0.9985121,0.0002058427,0.0006398518,0.0001846845,0.0002077706,0.0002496742],"domain_scores_gemma":[0.9985694,0.00008507823,0.0006519414,0.00008710331,0.0004809343,0.000125489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000705255,0.000257177,0.000805868,0.00007153806,0.0002442372,0.00004606283,0.0004234261,0.00006615359,0.9928206,0.000003355951,0.001568316,0.002987962],"study_design_scores_gemma":[0.00218039,0.0002716144,0.008224988,0.00005939565,0.0001839751,0.0007161401,0.0002500743,0.00003133247,0.9830441,0.00009413772,0.004787455,0.0001563232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9639145,0.03397321,0.001045151,0.0001145022,0.0005012858,0.0001172917,0.0002864334,0.000002836542,0.00004477695],"genre_scores_gemma":[0.9900985,0.008321873,0.0004393962,0.0003148619,0.0006592153,0.000003608714,0.00006661005,0.0000225224,0.00007334894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02618405,"threshold_uncertainty_score":0.6766922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059524179196153,"score_gpt":0.2662148559950919,"score_spread":0.2556196142031303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}