{"id":"W1552230212","doi":"10.1111/mmi.12223","title":"Hybrid sensor kinase <scp>PA</scp>1611 in <i><scp>P</scp>seudomonas aeruginosa</i> regulates transitions between acute and chronic infection through direct interaction with <scp>RetS</scp>","year":2013,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Manitoba","funders":"","keywords":"Pseudomonas aeruginosa; Biofilm; Biology; Chronic infection; Swarming motility; Microbiology; Virulence; Pathogenesis; Secretion; Gene; Motility; Type three secretion system; Immunology; Immune system; Bacteria; Genetics; Quorum sensing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009663974,0.0004071871,0.0002718841,0.0001190928,0.0001225855,0.000331847,0.0002884936,0.0002666192,0.001197281],"category_scores_gemma":[0.0001095772,0.0001436185,0.0002950733,0.0001516715,0.0002492625,0.0002722345,0.0003062069,0.0005772469,0.000744063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005562638,"about_ca_system_score_gemma":0.0002276084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006020602,"about_ca_topic_score_gemma":0.000816393,"domain_scores_codex":[0.9998857,0.00001940316,0.00001222977,0.00002731351,0.00003573991,0.00001949722],"domain_scores_gemma":[0.9999375,0.00001157887,0.00002226082,0.00000929833,0.000005516433,0.00001385888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006770289,0.00001670001,0.0001609988,0.00002638631,0.000003179081,0.00002721609,0.000006847244,0.0001069202,0.9988908,0.00007824128,0.00002596259,0.0005888648],"study_design_scores_gemma":[0.000009632388,0.0001280588,0.001540252,0.00000392928,0.000007322032,0.0001978649,0.0000174454,0.001572925,0.9937137,0.00004997144,0.002750843,0.000008156243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886782,0.0009300041,0.00792828,0.0001563118,0.00005649031,0.00005452016,0.0008201042,0.0001520479,0.001224061],"genre_scores_gemma":[0.9877406,0.0004662777,0.005665637,0.00005549103,0.00000848939,0.0000641594,0.001653681,0.00005340741,0.004292249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001197281,"threshold_uncertainty_score":0.00403595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005288444554042978,"score_gpt":0.2092058758405663,"score_spread":0.2039174312865233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}