{"id":"W1552565594","doi":"10.1111/cei.12404","title":"T helper type 2-polarized invariant natural killer T cells reduce disease severity in acute intra-abdominal sepsis","year":2014,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"National Institutes of Health; Royal College of Physicians and Surgeons of Canada; Ministère de l’Éducation, Gouvernement de l’Ontario; National Institute of Allergy and Infectious Diseases; London Health Sciences Centre; Canadian Institutes of Health Research; Lawson Health Research Institute","keywords":"Sepsis; Immunology; Natural killer T cell; Immune system; Proinflammatory cytokine; Spleen; Cytokine; Medicine; T cell; Inflammation; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000185268,0.0005899981,0.0005389762,0.0002568455,0.0001000124,0.0002371507,0.0001538838,0.000278263,0.0009043511],"category_scores_gemma":[0.0002464713,0.0001046138,0.0001680109,0.0001228133,0.0002463916,0.0002524843,0.0001870622,0.0009277508,0.0001954303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007675543,"about_ca_system_score_gemma":0.0001978891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001286236,"about_ca_topic_score_gemma":0.0002257095,"domain_scores_codex":[0.9999007,0.00003077528,0.000008921685,0.00001026844,0.00001711711,0.00003213895],"domain_scores_gemma":[0.9998368,0.0000149734,0.00003537483,0.00001362881,0.00001853043,0.00008074792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.008714796,0.001769038,0.001252369,0.0001928249,0.00002966539,0.0001026769,0.00004684366,0.0004624181,0.9568073,0.0001150719,0.0003287394,0.03017824],"study_design_scores_gemma":[0.002846781,0.06871638,0.04642658,0.0001279154,0.0002253448,0.0007951123,0.0002324377,0.00392245,0.86923,0.0006776012,0.006763597,0.00003580871],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957901,0.001776411,0.001181411,0.0001411445,0.00008144687,0.00004200634,0.000059055,0.00009841088,0.0008300398],"genre_scores_gemma":[0.9953674,0.001301149,0.001299742,0.0001567119,0.00006070757,0.00004928252,0.0001556062,0.00002239592,0.001587024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009043511,"threshold_uncertainty_score":0.003025353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02190338531155201,"score_gpt":0.3268850347347444,"score_spread":0.3049816494231924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}