{"id":"W1552565594","doi":"10.1111/cei.12404","title":"T helper type 2-polarized invariant natural killer T cells reduce disease severity in acute intra-abdominal sepsis","year":2014,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"National Institutes of Health; Royal College of Physicians and Surgeons of Canada; Ministère de l’Éducation, Gouvernement de l’Ontario; National Institute of Allergy and Infectious Diseases; London Health Sciences Centre; Canadian Institutes of Health Research; Lawson Health Research Institute","keywords":"Sepsis; Immunology; Natural killer T cell; Immune system; Proinflammatory cytokine; Spleen; Cytokine; Medicine; T cell; Inflammation; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005614558,0.0003751473,0.0007270401,0.0001690745,0.0002090451,0.0000333563,0.0004155012,0.0005900398,0.004491268],"category_scores_gemma":[0.0003870747,0.0003403174,0.000319071,0.0002105186,0.0007104257,0.0002722826,0.0003195891,0.001373369,0.003642702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001665798,"about_ca_system_score_gemma":0.0001020671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001676985,"about_ca_topic_score_gemma":0.000008134475,"domain_scores_codex":[0.9961842,0.001345154,0.001063267,0.0007298552,0.00005740247,0.0006201541],"domain_scores_gemma":[0.9985229,0.0004333832,0.0002571591,0.0006142178,0.00009673405,0.00007558375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00742226,0.001188634,0.000936183,0.000004827861,0.0003984012,0.00002124117,0.0002698369,8.575975e-7,0.9766497,0.0003363569,0.01059168,0.00218],"study_design_scores_gemma":[0.01169707,0.001994055,0.03788615,0.00008662786,0.0001875716,0.0001518853,0.0009910342,0.0002031436,0.7081,0.0001496448,0.2375674,0.0009854236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9498811,0.00498282,0.00008119778,0.0009149085,0.04275766,0.0004115086,0.000003629503,0.0001234787,0.000843741],"genre_scores_gemma":[0.9836591,0.0003507307,0.0001481358,0.00248063,0.0001241721,0.00004571591,0.0002413341,0.0000373576,0.01291282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2685497,"threshold_uncertainty_score":0.9999049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02190338531155201,"score_gpt":0.3268850347347444,"score_spread":0.3049816494231924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}