{"id":"W1553789387","doi":"10.1002/jgm.2675","title":"Strength and muscle specificity of a compact promoter derived from the slow troponin I gene in the context of episomal (gutless adenovirus) and integrating (lentiviral) vectors","year":2012,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital; National Research Council Canada; Université de Montréal; Biotechnology Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Context (archaeology); Genetic enhancement; Biology; Myogenesis; Viral vector; Enhancer; Molecular biology; Myocyte; In vivo; Cell culture; Gene silencing; Actin; Plasmid; Skeletal muscle; Gene; Cell biology; Gene expression; Genetics; Anatomy; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003132943,0.0002589399,0.0001382447,0.0001442178,0.00008734435,0.0002942008,0.000206865,0.0001712646,0.0006680485],"category_scores_gemma":[0.0001674473,0.0001251456,0.0001562363,0.00009394869,0.0002916891,0.0001550924,0.0002075913,0.0003490971,0.0001764458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002384403,"about_ca_system_score_gemma":0.0002250264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002980338,"about_ca_topic_score_gemma":0.0003984768,"domain_scores_codex":[0.9998088,0.00002564796,0.00002410481,0.00006017907,0.00005659018,0.00002463501],"domain_scores_gemma":[0.9998115,0.00003556797,0.00006302364,0.00002168724,0.00002407023,0.00004423163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003334098,0.000007027889,0.0001714044,0.00001106666,0.000001513356,0.000006526468,0.000005996671,0.00001744085,0.9993968,0.00003740125,0.000004550312,0.0003069036],"study_design_scores_gemma":[0.00001701677,0.0003312963,0.004665007,0.000008413337,0.00001990095,0.0002258333,0.00001822446,0.0006959148,0.9928261,0.00002606702,0.001162301,0.000003970614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953763,0.0005949964,0.00327946,0.0000191901,0.00001100372,0.00001832523,0.0001150299,0.00002275098,0.0005628688],"genre_scores_gemma":[0.9951361,0.0002921104,0.002985794,0.00001725373,0.000007315582,0.0000254647,0.0004253721,0.00001853328,0.001092006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006680485,"threshold_uncertainty_score":0.002234817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01659305370152409,"score_gpt":0.2542877305620077,"score_spread":0.2376946768604836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}