{"id":"W1553789387","doi":"10.1002/jgm.2675","title":"Strength and muscle specificity of a compact promoter derived from the slow troponin I gene in the context of episomal (gutless adenovirus) and integrating (lentiviral) vectors","year":2012,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital; National Research Council Canada; Université de Montréal; Biotechnology Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Context (archaeology); Genetic enhancement; Biology; Myogenesis; Viral vector; Enhancer; Molecular biology; Myocyte; In vivo; Cell culture; Gene silencing; Actin; Plasmid; Skeletal muscle; Gene; Cell biology; Gene expression; Genetics; Anatomy; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008807527,0.0001077904,0.0002538917,0.00002462108,0.00005314546,0.000002732671,0.0002054822,0.00005308818,0.00001506644],"category_scores_gemma":[0.0001534636,0.00004624201,0.00004269775,0.00005646747,0.0004746452,0.000007321091,0.00003723998,0.0001816787,1.013148e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004554011,"about_ca_system_score_gemma":0.00002420629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003129365,"about_ca_topic_score_gemma":0.0001452575,"domain_scores_codex":[0.998942,0.0003920345,0.000335555,0.00007214789,0.0001277898,0.0001305089],"domain_scores_gemma":[0.999207,0.000202619,0.0003316226,0.000171807,0.00005091561,0.00003605271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004202096,0.00008939139,0.02316009,0.000008863461,0.00006637975,7.968914e-7,0.0053822,0.000003301426,0.9679702,0.00001793024,0.0001513621,0.002729268],"study_design_scores_gemma":[0.001517831,0.000751993,0.6483084,0.00007635073,0.0001036861,0.00003121802,0.01316455,0.00002899515,0.3357161,0.0001069895,0.000126536,0.00006731963],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900665,0.008613476,0.0001701823,0.0009098696,0.00007341481,0.0001130173,0.00001124791,5.646244e-7,0.00004172871],"genre_scores_gemma":[0.998704,0.0007499855,0.00006314761,0.0001958083,0.000269861,6.399557e-7,0.000007404454,0.000006084999,0.000003042584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6322541,"threshold_uncertainty_score":0.1885695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01659305370152409,"score_gpt":0.2542877305620077,"score_spread":0.2376946768604836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}