{"id":"W1554028202","doi":"10.1002/jbmr.2150","title":"Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis, while Oleic Acid-Induced Triglyceride Formation Prevents It","year":2013,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health; American Heart Association","keywords":"Osteoclast; RANKL; Endocrinology; Internal medicine; Chemistry; Triglyceride; Bone remodeling; Oleic acid; Fatty acid; Activator (genetics); Receptor; Biochemistry; Biology; Medicine; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001652848,0.0006951115,0.0004706803,0.0005342942,0.0001860967,0.0003963975,0.0002663956,0.0003878386,0.002284839],"category_scores_gemma":[0.0001129658,0.0002554021,0.0006190909,0.0003266749,0.0003603153,0.0002583146,0.0003680692,0.0007315804,0.0006417973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003106327,"about_ca_system_score_gemma":0.0004387464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006943432,"about_ca_topic_score_gemma":0.00130849,"domain_scores_codex":[0.9997972,0.00002398382,0.00003559593,0.0000430228,0.00004915355,0.0000510471],"domain_scores_gemma":[0.9997702,0.00001650507,0.00007734374,0.00002567637,0.00002274322,0.00008744274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005694253,0.00006223207,0.0003409516,0.00008987445,0.00001725221,0.00007278949,0.000008381644,0.00003266066,0.9968911,0.0001471502,0.0000443358,0.001723856],"study_design_scores_gemma":[0.0001467694,0.0007814202,0.006654917,0.00002537101,0.00008589288,0.0007156033,0.00002820992,0.0002559601,0.9842711,0.0001701477,0.006854221,0.00001044502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828455,0.006436099,0.006328454,0.0003092416,0.0001609036,0.00006557847,0.001331402,0.0002666178,0.002256267],"genre_scores_gemma":[0.9802052,0.005771364,0.005121415,0.0001482232,0.0000372129,0.0001012677,0.002049125,0.00006924256,0.006496947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002284839,"threshold_uncertainty_score":0.007643521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03425272651080879,"score_gpt":0.3249783778557072,"score_spread":0.2907256513448984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}