{"id":"W1554028202","doi":"10.1002/jbmr.2150","title":"Palmitic Acid and DGAT1 Deficiency Enhance Osteoclastogenesis, while Oleic Acid-Induced Triglyceride Formation Prevents It","year":2013,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health; American Heart Association","keywords":"Osteoclast; RANKL; Endocrinology; Internal medicine; Chemistry; Triglyceride; Bone remodeling; Oleic acid; Fatty acid; Activator (genetics); Receptor; Biochemistry; Biology; Medicine; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005913517,0.0001142043,0.0002071647,0.000149627,0.0001287236,0.00008656771,0.00009567267,0.00009116681,0.00003197681],"category_scores_gemma":[0.0002929667,0.00008871427,0.00007106774,0.0001248522,0.00007995577,0.00005557223,0.0001129412,0.0001553018,0.000008372444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001077063,"about_ca_system_score_gemma":0.0001290919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003530214,"about_ca_topic_score_gemma":0.00001865003,"domain_scores_codex":[0.9986574,0.0001452109,0.00036117,0.0001714497,0.000355051,0.0003096845],"domain_scores_gemma":[0.9991088,0.00002438414,0.0001337488,0.0001485113,0.0003487308,0.0002358208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001329576,0.00007142588,0.0005006781,0.00005495014,0.00001245194,0.000007200141,0.00006471545,6.474536e-7,0.97925,0.00000953269,0.005598754,0.01429667],"study_design_scores_gemma":[0.001344593,0.001069391,0.01695673,0.00008250283,0.00003678103,0.0002418629,0.0004627082,0.00003444862,0.9729559,0.0002412285,0.006392758,0.0001810445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855101,0.01323655,0.0001118068,0.0005546432,0.00005913362,0.0001808829,0.00000643125,0.000001852287,0.0003386154],"genre_scores_gemma":[0.9957862,0.00288816,0.0002509215,0.0001229552,0.0002101879,0.00001644712,0.00000908156,0.00001064419,0.0007054037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01645605,"threshold_uncertainty_score":0.3617663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03425272651080879,"score_gpt":0.3249783778557072,"score_spread":0.2907256513448984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}