{"id":"W1554789506","doi":"10.1002/stem.1564","title":"Critical Components of the Pluripotency Network Are Targets for the p300/CBP Interacting Protein (p/CIP) in Embryonic Stem Cells","year":2013,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Homeobox protein NANOG; Coactivator; KLF4; Gene knockdown; Chromatin immunoprecipitation; SOX2; Embryonic stem cell; Cell biology; Rex1; Induced pluripotent stem cell; Transcription factor; Molecular biology; Nuclear receptor; Gene; Gene expression; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009484143,0.0003910439,0.0002629453,0.0004281466,0.0002393037,0.0003120426,0.0001985347,0.000150535,0.001062697],"category_scores_gemma":[0.0001510041,0.0002162729,0.0002540304,0.0003594274,0.000201242,0.0002118038,0.0002820567,0.000369711,0.0004991995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004445556,"about_ca_system_score_gemma":0.0003425112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001317987,"about_ca_topic_score_gemma":0.001832436,"domain_scores_codex":[0.9998517,0.000008884195,0.00001201829,0.00004657263,0.00005631754,0.00002449587],"domain_scores_gemma":[0.9999088,0.00001103017,0.00002911335,0.000007352813,0.00002059378,0.00002307265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004906466,0.000005355053,0.0007870174,0.00004424835,0.000004072325,0.00006067478,0.00001062232,0.00007347231,0.9966948,0.0001062998,0.00007678244,0.002087576],"study_design_scores_gemma":[0.00002394423,0.0001094255,0.1083874,0.0000245135,0.00004965832,0.0005352507,0.00006747558,0.003744257,0.8783932,0.0003872382,0.008261433,0.00001612348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9730405,0.004726153,0.01456845,0.0001533671,0.00003508164,0.0000577135,0.004254794,0.0005715239,0.002592547],"genre_scores_gemma":[0.9842961,0.001415595,0.005508013,0.00008167332,0.00001152645,0.00006918614,0.005691688,0.00006438779,0.002861761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001317987,"threshold_uncertainty_score":0.003555059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01974797724996289,"score_gpt":0.2633301725154333,"score_spread":0.2435821952654704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}