{"id":"W1555962635","doi":"10.1007/978-3-7091-6139-5_22","title":"Neurotrophic factors and Alzheimer’s disease: are we focusing on the wrong molecule?","year":2002,"lang":"en","type":"article","venue":"Journal of neural transmission. Supplementum","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":124,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Basal forebrain; Nucleus basalis; Cholinergic neuron; Neurotrophic factors; Neuroscience; Cholinergic; Brain-derived neurotrophic factor; Hippocampus; Neurotrophin; Internal medicine; Endocrinology; Biology; Psychology; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001136286,0.0005883861,0.001093338,0.0006406249,0.000750172,0.001894475,0.001175867,0.002460713,0.007041289],"category_scores_gemma":[0.002981697,0.0002235881,0.0004531341,0.000364705,0.001703137,0.003736689,0.001008379,0.003663622,0.002414647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001063683,"about_ca_system_score_gemma":0.001372151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002780901,"about_ca_topic_score_gemma":0.004999369,"domain_scores_codex":[0.9997028,0.0000640508,0.00004970076,0.00002711828,0.0001011255,0.00005514062],"domain_scores_gemma":[0.9982407,0.0005070697,0.0001892713,0.000148264,0.0006585128,0.0002560482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001242296,0.0001126157,0.001369808,0.002001594,0.000150581,0.0008522113,0.0004262633,0.00009906846,0.01043183,0.02211794,0.7277845,0.2334113],"study_design_scores_gemma":[0.0001080795,0.0001866371,0.003393732,0.0008224471,0.0001262024,0.00165098,0.0007314319,0.0001195572,0.00254917,0.02701981,0.9632505,0.00004150235],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.009438124,0.5196291,0.0006864535,0.3579498,0.1044626,0.0000141305,0.000324854,0.00006005951,0.00743479],"genre_scores_gemma":[0.07008144,0.6906214,0.002419027,0.06317563,0.1129724,0.0000700137,0.0004924662,0.00006550411,0.06010213],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.007041289,"threshold_uncertainty_score":0.0235554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207993809630127,"score_gpt":0.2944190279217132,"score_spread":0.1736196469587005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}