{"id":"W1556965300","doi":"10.1002/cm.21148","title":"Actin and microtubules play distinct roles in governing the anisotropic deformation of cell nuclei in response to substrate strain","year":2013,"lang":"en","type":"article","venue":"Cytoskeleton","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Microtubule; Nucleus; Anisotropy; Deformation (meteorology); Biophysics; Biology; Actin; Strain (injury); Cell biology; Cell nucleus; Materials science; Physics; Anatomy; Composite material; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001588927,0.0001981746,0.0001429693,0.0001966475,0.0002514453,0.0004342421,0.0001628886,0.0002537182,0.0003946584],"category_scores_gemma":[0.00020325,0.0002109034,0.000103228,0.0001136511,0.0003264299,0.0002872539,0.0001734574,0.0001770709,0.00009214587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002803005,"about_ca_system_score_gemma":0.0001861663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007577531,"about_ca_topic_score_gemma":0.00218476,"domain_scores_codex":[0.9998802,0.00001966664,0.000009467337,0.0000224417,0.00003081535,0.0000373984],"domain_scores_gemma":[0.9998828,0.00002384111,0.00003645271,0.00001038286,0.00001905164,0.00002738464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007223961,0.00001156053,0.001310019,0.00001860687,0.000003936271,0.00004760915,0.00002989183,0.0003179677,0.995666,0.0004188205,0.00001572493,0.002087578],"study_design_scores_gemma":[0.00002661056,0.0002098071,0.1330014,0.0000187658,0.00002547901,0.0003690959,0.0003643304,0.007906307,0.8549785,0.0007572785,0.002310024,0.0000324227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956936,0.0007724037,0.00236843,0.00005323746,0.000008621681,0.000007286187,0.00003519368,0.00001197928,0.001049294],"genre_scores_gemma":[0.9982331,0.0004920642,0.0006319197,0.00001085864,0.00000292429,0.000008857404,0.00002211604,0.000002459399,0.0005956735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007577531,"threshold_uncertainty_score":0.00203377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005450717757302212,"score_gpt":0.2161579675147793,"score_spread":0.2107072497574771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}