{"id":"W1557218655","doi":"10.1111/j.1365-2958.2010.07192.x","title":"<i>N</i>‐acetyllactosamine‐induced retraction of bundle‐forming pili regulates virulence‐associated gene expression in enteropathogenic <i>Escherichia coli</i>","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Alberta Glycomics Centre; Fondation pour la Recherche Médicale","keywords":"Enteropathogenic Escherichia coli; Pilus; Biology; Fimbriae Proteins; Microbiology; Periplasmic space; Operon; Bacterial adhesin; Escherichia coli; Virulence; Chaperone (clinical); Downregulation and upregulation; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008899169,0.0002335739,0.0001334025,0.0001000823,0.0001044399,0.0002603346,0.00007283884,0.0001404476,0.0004841612],"category_scores_gemma":[0.0001077963,0.00008688265,0.000122949,0.0000849467,0.0001671573,0.0001072577,0.0001202253,0.0002962815,0.0002356642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003435991,"about_ca_system_score_gemma":0.0001249788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009508854,"about_ca_topic_score_gemma":0.001107529,"domain_scores_codex":[0.9999135,0.00001645027,0.000006713468,0.00001594665,0.00002179668,0.00002563563],"domain_scores_gemma":[0.9999465,0.000009855289,0.00001537031,0.000005124044,0.000008755484,0.00001447983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004215077,0.000009822725,0.0001304905,0.000007895461,7.90995e-7,0.00001659409,0.000005345894,0.00001455661,0.9995627,0.00001450575,0.000009611099,0.0001853797],"study_design_scores_gemma":[0.000008197974,0.0001631949,0.03634818,0.000005272832,0.000008536168,0.0001693501,0.00004988612,0.0009951273,0.9610156,0.00004264545,0.001189216,0.000004621385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976807,0.0005193726,0.0008120334,0.00005785326,0.0000108306,0.0000096413,0.0001576653,0.00002896739,0.0007229758],"genre_scores_gemma":[0.9958917,0.000404041,0.001061626,0.00006300921,0.000007784581,0.00001842662,0.0004801591,0.0000162462,0.002056943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009508854,"threshold_uncertainty_score":0.002493024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007735592790899737,"score_gpt":0.2442658125300916,"score_spread":0.2365302197391918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}