{"id":"W1557380779","doi":"10.1002/9783527621224.ch11","title":"Membrane Protein Structure and Conformational Change Probed using Fourier Transform Infrared Spectroscopy","year":2007,"lang":"en","type":"other","venue":"","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Side chain; Fourier transform infrared spectroscopy; Chemistry; Crystallography; Spectroscopy; Amide; Protein structure; Membrane protein; Membrane; Infrared spectroscopy; Integral membrane protein; Hydrogen bond; Methylene; Conformational change; Attenuated total reflection; Lipid bilayer; Biophysics; Stereochemistry; Molecule; Organic chemistry; Biochemistry; Biology; Chemical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001022943,0.0002439019,0.0001283072,0.0002652452,0.0001448093,0.0003262481,0.0002406901,0.0002838525,0.009996567],"category_scores_gemma":[0.00007600935,0.0001205363,0.0001403587,0.000244156,0.0001305937,0.0003859784,0.0001482584,0.0003684853,0.002981929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002161564,"about_ca_system_score_gemma":0.00009701026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004133033,"about_ca_topic_score_gemma":0.0006452113,"domain_scores_codex":[0.9999256,0.000003660992,0.000002393959,0.00001452143,0.00004538382,0.000008385193],"domain_scores_gemma":[0.9999758,0.000005689606,0.000003088622,0.000002843869,0.000009763115,0.000002756974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003799655,0.00003961985,0.0001666045,0.00007471323,0.000002679736,0.00004687605,0.00003591261,0.0001916042,0.9570143,0.001690742,0.001785999,0.03891303],"study_design_scores_gemma":[0.00000645733,0.00008414243,0.004976164,0.0000307965,0.000007950275,0.0002420324,0.00007517459,0.002081187,0.9315621,0.0007368597,0.06018344,0.00001359593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4951991,0.01962789,0.1317626,0.002120428,0.000798276,0.0001819287,0.003029836,0.002803056,0.3444769],"genre_scores_gemma":[0.4106981,0.03316609,0.1064193,0.0007490309,0.0001636838,0.0001743623,0.003808779,0.0005507636,0.4442698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009996567,"threshold_uncertainty_score":0.03344184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462022057726647,"score_gpt":0.273735007110874,"score_spread":0.2591147865336075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}