{"id":"W1558188448","doi":"10.1089/thy.2013.0370","title":"Long-Term Efficacy of Modified-Release Recombinant Human Thyrotropin Augmented Radioiodine Therapy for Benign Multinodular Goiter: Results from a Multicenter, International, Randomized, Placebo-Controlled, Dose-Selection Study","year":2013,"lang":"en","type":"article","venue":"Thyroid","topic":"Thyroid and Parathyroid Surgery","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Hamilton General Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Radioiodine therapy; Multinodular goiter; Medicine; Placebo; Recombinant DNA; Selection (genetic algorithm); Term (time); Goiter; Randomized controlled trial; Internal medicine; Thyroid; Pathology; Chemistry; Thyroid cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001338776,0.0006507346,0.002224799,0.0005016744,0.0002387553,0.0001121654,0.000356349,0.0002254511,0.0002028355],"category_scores_gemma":[0.001117656,0.000500334,0.0009704035,0.0002515814,0.0001733742,0.0002889475,0.00007838006,0.0004159085,0.00007565244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900939,"about_ca_system_score_gemma":0.00009718678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001427016,"about_ca_topic_score_gemma":0.00005995957,"domain_scores_codex":[0.9948872,0.0006732412,0.002158433,0.0009806261,0.0006744402,0.0006261156],"domain_scores_gemma":[0.9954432,0.001767248,0.001038167,0.0008463992,0.0005942204,0.0003107148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7904792,0.009245491,0.004291106,0.00003528779,0.002869956,0.00005775864,0.002403287,0.0002308351,0.1807187,0.00006170748,0.006150562,0.00345616],"study_design_scores_gemma":[0.9437109,0.00219536,0.03085176,0.0001822534,0.0005515672,0.00001712909,0.0002316352,0.01274434,0.00869415,0.00004726793,0.0002609778,0.0005126284],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791105,0.001746758,0.0009158968,0.0005716585,0.001142483,0.0157498,0.0001340273,0.0002110215,0.0004178084],"genre_scores_gemma":[0.9922443,0.0005722864,0.0006216398,0.0002378888,0.0006016531,0.001876705,0.001036575,0.0001073745,0.002701556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1720245,"threshold_uncertainty_score":0.9997448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266693182081169,"score_gpt":0.3010471636723051,"score_spread":0.2743778454641881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}