{"id":"W1558516295","doi":"10.1023/a:1022531403741","title":"Reassessing Models of Hepatic Extraction","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Physics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Alberta Heritage Foundation for Medical Research","keywords":"IVIVC; Context (archaeology); Dispersion (optics); In vivo; Computer science; Biological system; Chemistry; Pharmacokinetics; Bioinformatics; Physics; Biology; Biopharmaceutics Classification System","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009759062,0.0001375609,0.0003760123,0.00004942954,0.00007559738,0.000008311524,0.0001682813,0.0001899234,0.0001640624],"category_scores_gemma":[0.0001394172,0.00009860226,0.000211936,0.0001704526,0.0001367002,0.0001571243,0.00002172023,0.0005927747,0.00000646755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002535098,"about_ca_system_score_gemma":0.00008809438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001261623,"about_ca_topic_score_gemma":8.572717e-8,"domain_scores_codex":[0.998373,0.0005693035,0.0005715539,0.0001115687,0.0001592593,0.0002153085],"domain_scores_gemma":[0.9985108,0.0003341392,0.0006554987,0.00008806173,0.0002529407,0.0001585323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002759179,0.001099009,0.00436419,0.00003039063,0.0002198123,0.00003487222,0.0002008203,0.01228236,0.8991575,0.01962943,0.0005177591,0.06218797],"study_design_scores_gemma":[0.002622415,0.0005202453,0.002413819,0.00004077567,0.0004021489,0.0001794426,0.0001526789,0.01064186,0.7171363,0.2261275,0.03940794,0.0003549233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976532,0.00201055,0.01354687,0.00006606253,0.001126504,0.00008398626,0.00000945428,0.000008950984,0.006615564],"genre_scores_gemma":[0.9946634,0.00193151,0.002672685,0.0003496388,0.0003420122,0.000001511886,0.000001471603,0.000008827169,0.00002890764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2064981,"threshold_uncertainty_score":0.4020883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2862650852246321,"score_gpt":0.4778820788628274,"score_spread":0.1916169936381952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}