{"id":"W1558682953","doi":"10.4049/jimmunol.192.supp.124.4","title":"Tyrosine phosphorylation of IFITM3 blocks an endocytic motif necessary for its complete influenza virus restriction (INM8P.438)","year":2014,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"FYN; Phosphorylation; Cell biology; Endocytosis; Tyrosine phosphorylation; Endocytic cycle; Endosome; Tyrosine; Biology; Tyrosine kinase; Population; Protein tyrosine phosphatase; Cytoplasm; Src family kinase; Proto-oncogene tyrosine-protein kinase Src; Influenza A virus; Virology; Cell; Virus; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001584503,0.0002665742,0.0001711864,0.00009435198,0.0001632322,0.0001368016,0.000260783,0.0002782333,0.002465321],"category_scores_gemma":[0.000146506,0.0001008035,0.0001998495,0.00006503474,0.0002241358,0.0001333551,0.0001451096,0.00050123,0.0004628651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000313398,"about_ca_system_score_gemma":0.0002157862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007157841,"about_ca_topic_score_gemma":0.0006124084,"domain_scores_codex":[0.9998682,0.0000302134,0.00001552872,0.00001587071,0.00002719,0.00004307233],"domain_scores_gemma":[0.9998994,0.00002738232,0.00002571526,0.0000147987,0.000007588931,0.00002502491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001576769,0.00003746808,0.00006785,0.00001437269,0.000002917197,0.00003352581,0.000004450146,0.00004346879,0.9991013,0.0001398344,0.00003433225,0.0003629311],"study_design_scores_gemma":[0.00003148656,0.0002893505,0.001439766,0.000004738561,0.000006516684,0.0002146029,0.000008210864,0.0009384647,0.9957501,0.00004982347,0.001264878,0.000002089885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966077,0.000337358,0.001230339,0.0000966121,0.00003052838,0.00001975777,0.0002135812,0.0000423112,0.001421884],"genre_scores_gemma":[0.9970196,0.0001551343,0.001394738,0.00003545096,0.000005975171,0.00002657135,0.0003639394,0.00001774902,0.0009808709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002465321,"threshold_uncertainty_score":0.008247256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0298245151018465,"score_gpt":0.2751787799707864,"score_spread":0.2453542648689399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}