{"id":"W1558688164","doi":"10.1111/j.1471-4159.2006.04304.x","title":"A comparison of the glutamate release inhibition and anti‐allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain","year":2006,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Pfizer","keywords":"Riluzole; Gabapentin; Lamotrigine; Neuropathic pain; Pharmacology; Microdialysis; Nociception; Glutamate receptor; Anticonvulsant; Anesthesia; Medicine; Chemistry; Epilepsy; Internal medicine; Central nervous system; Receptor; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004064255,0.0000979707,0.00038694,0.00006102008,0.00001464055,0.000003309375,0.00004283342,0.00005238592,8.889164e-7],"category_scores_gemma":[0.0003154196,0.0000697338,0.00007659927,0.0001078553,0.00005938336,0.00003635761,0.00003023775,0.0001946599,3.270964e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001048945,"about_ca_system_score_gemma":0.00004884873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008749747,"about_ca_topic_score_gemma":9.585438e-7,"domain_scores_codex":[0.9989868,0.0001280115,0.0004830774,0.00009222187,0.0002190085,0.00009081516],"domain_scores_gemma":[0.9990287,0.0001595049,0.0005657718,0.0001126202,0.00008672712,0.00004670293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001204628,0.0005512787,0.05629797,0.001237802,0.0000142693,0.00007596658,0.00005067035,0.0002360802,0.9411634,0.000008433197,0.00002278899,0.0002209244],"study_design_scores_gemma":[0.002989182,0.0003422946,0.1067787,0.001481961,0.0001573949,0.0001758872,0.00002524587,0.02690036,0.8608541,0.000238698,0.000002624775,0.0000535503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986567,0.000787321,0.0003053835,0.00008487191,0.00001798144,0.0001053969,0.000003045934,0.000002071308,0.00003716077],"genre_scores_gemma":[0.999598,0.0001169743,0.0002013123,0.00003633907,0.0000166397,8.227919e-7,9.882049e-7,0.000009117946,0.00001984175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08030927,"threshold_uncertainty_score":0.2843662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008010939178084202,"score_gpt":0.2479923123101714,"score_spread":0.2399813731320872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}