{"id":"W1559437441","doi":"10.2165/0148581-200911010-00012","title":"Pediatric Clinical Pharmacology Studies in Chagas Disease","year":2009,"lang":"en","type":"review","venue":"Pediatric Drugs","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"","keywords":"Benznidazole; Nifurtimox; Medicine; Chagas disease; Pharmacotherapy; Disease; Population; Intensive care medicine; Drug; Asymptomatic; Trypanosoma cruzi; Pharmacology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002764995,0.0005650275,0.002811105,0.001340173,0.0001010568,0.00002320311,0.0004707216,0.0003747407,0.0002504106],"category_scores_gemma":[0.001365769,0.0004437516,0.0009895972,0.00225435,0.0001727724,0.00009251269,0.0002596774,0.001590911,0.001254292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003801055,"about_ca_system_score_gemma":0.002503877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004508266,"about_ca_topic_score_gemma":0.000001227221,"domain_scores_codex":[0.9953604,0.0004740196,0.001723352,0.0009467772,0.00059616,0.00089923],"domain_scores_gemma":[0.9962333,0.001370338,0.0004572866,0.0007177067,0.0002120223,0.001009288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005531168,0.001099632,0.002809607,0.02283508,0.0001865124,0.0004979203,0.00005716483,1.103985e-7,2.518519e-8,0.00006252427,0.227202,0.7451941],"study_design_scores_gemma":[0.00121971,0.0001923703,0.01403901,0.0003832947,0.004609677,0.0000380471,0.00002232864,0.000001923203,1.180198e-8,0.00006353683,0.9790574,0.0003726397],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003685002,0.9941749,0.00000164612,0.0006947712,0.001203065,0.002146114,0.0001145588,0.0001215399,0.001174915],"genre_scores_gemma":[0.00006885873,0.9798378,0.00009456786,0.0004108581,0.01656947,0.0004991256,0.0001979569,0.00007027475,0.002251084],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7518555,"threshold_uncertainty_score":0.9998014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2470938591868974,"score_gpt":0.5531983151902072,"score_spread":0.3061044560033098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}