{"id":"W1560033717","doi":"10.4049/jimmunol.1500558","title":"Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Gene; Gene expression; Biology; Differential (mechanical device); Expression (computer science); Cell biology; Genetics; Computer science; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222358,0.0001359741,0.0002098623,0.0005062599,0.0001387513,0.0003522515,0.0001234269,0.0002046497,0.001069995],"category_scores_gemma":[0.0002481298,0.0001215072,0.0003242985,0.0001974674,0.000229897,0.0002031556,0.0003560538,0.0004111663,0.0002873829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001160567,"about_ca_system_score_gemma":0.00009690873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001304948,"about_ca_topic_score_gemma":0.0002114466,"domain_scores_codex":[0.9997681,0.00002322286,0.00002432621,0.00005556994,0.00006833499,0.00006049827],"domain_scores_gemma":[0.9996755,0.00007012082,0.00007981287,0.00004475124,0.00004886705,0.00008087754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009058353,0.000009804905,0.001199533,0.00001956435,0.000003988321,0.00004691231,0.00002213372,0.00001585372,0.9979511,0.0000448833,0.000005756123,0.0005899118],"study_design_scores_gemma":[0.00002237549,0.0003881683,0.2466164,0.00001479088,0.00003671585,0.00145459,0.0002814593,0.0007864619,0.7482038,0.0001735771,0.002006972,0.00001464028],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969399,0.0008269284,0.001109074,0.00001619739,0.000007284587,0.0000110102,0.0004864048,0.00001969919,0.0005834999],"genre_scores_gemma":[0.9962131,0.000337611,0.001031173,0.00003459959,0.000009360959,0.0000245333,0.001093462,0.00001157528,0.001244718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001069995,"threshold_uncertainty_score":0.003579497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531313707167972,"score_gpt":0.2558223757780035,"score_spread":0.2405092387063238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}