{"id":"W1560205757","doi":"10.1002/14356007.c13_c01.pub2","title":"HIV and AIDS Therapeutics","year":2007,"lang":"en","type":"reference-entry","venue":"Ullmann's Encyclopedia of Industrial Chemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Enfuvirtide; Reverse transcriptase; Virology; Protease; Nucleoside; Peptidomimetic; Nucleoside analogue; Protease inhibitor (pharmacology); Biology; Virus; Medicine; Peptide; Enzyme; RNA; Viral load; Immunology; Biochemistry; Antiretroviral therapy; Antigen; Gp41","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003152445,0.000573763,0.0008992413,0.0001376888,0.0001328728,0.00002045852,0.0004646642,0.002893819,0.002151357],"category_scores_gemma":[0.0002003633,0.0004910798,0.0002089056,0.0001868859,0.0005614236,0.00004872437,0.0002497353,0.002091162,0.0003119208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001295034,"about_ca_system_score_gemma":0.0007679043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008146078,"about_ca_topic_score_gemma":0.000004288302,"domain_scores_codex":[0.997622,0.0001092617,0.0006855487,0.0006272182,0.0001859053,0.0007700396],"domain_scores_gemma":[0.9983776,0.0004086911,0.0003740545,0.0005693475,0.0001489588,0.0001213889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008261757,0.0006321077,0.01044009,0.0005850394,0.002414926,0.0001280693,0.0002669152,3.375161e-7,0.001748295,0.00004229327,0.5967562,0.3861596],"study_design_scores_gemma":[0.003186457,0.0002131234,0.00007291503,0.0003927031,0.0003097707,0.00005598099,0.0001724602,6.286216e-8,0.01561816,0.00003631483,0.9795278,0.0004142401],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.05404589,0.04461985,0.00000770008,0.000147899,0.001664957,0.0005932068,0.003015176,0.00008973426,0.8958156],"genre_scores_gemma":[0.01839098,0.2157907,0.0001123741,0.00006261012,0.002613795,0.00008395068,0.01176599,0.0001307935,0.7510488],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.3857453,"threshold_uncertainty_score":0.9997541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.035231535647067,"score_gpt":0.2771234563602386,"score_spread":0.2418919207131716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}