{"id":"W1560285111","doi":"10.1111/j.1751-7915.2010.00185.x","title":"Mining bacterial genomes for novel arylesterase activity","year":2010,"lang":"en","type":"article","venue":"Microbial Biotechnology","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Health and Long Term Care; Ontario Institute for Cancer Research; University of Toronto","funders":"National Institutes of Health; Ontario Genomics; Ontario Genomics Institute; Genome Canada","keywords":"Streptomyces avermitilis; Esterase; Biochemistry; Pseudomonas putida; Enzyme; Arylesterase; Rhodopseudomonas palustris; Escherichia coli; Bacterial genome size; Genome; Gene; Biology; Chemistry; Bacteria; Streptomyces; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004958475,0.0007665057,0.0009256186,0.002444386,0.0003853073,0.001190249,0.0004384573,0.0006453804,0.0009156365],"category_scores_gemma":[0.001463819,0.0003033914,0.0007061276,0.004344318,0.0001870506,0.0005429079,0.000551571,0.0004815634,0.0008019357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004147896,"about_ca_system_score_gemma":0.000754255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001552759,"about_ca_topic_score_gemma":0.002213777,"domain_scores_codex":[0.9996029,0.0000489174,0.00004656118,0.0001163829,0.000111044,0.00007418391],"domain_scores_gemma":[0.9994543,0.000145985,0.0001791443,0.00003706443,0.0001067381,0.00007663227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007288639,0.0001842716,0.03947686,0.00233244,0.0001820633,0.001372072,0.000538451,0.001531723,0.8904831,0.0005633916,0.001250183,0.0613566],"study_design_scores_gemma":[0.0002222963,0.001100129,0.4860733,0.000810602,0.001826368,0.01001164,0.002957626,0.02114704,0.37441,0.002415234,0.09879483,0.0002308901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9396576,0.01002026,0.01881762,0.0004642195,0.00005306983,0.0002041872,0.02777047,0.0005537931,0.002458742],"genre_scores_gemma":[0.8159624,0.009113505,0.07526529,0.00026844,0.00004647271,0.0002215907,0.0968172,0.00023051,0.002074586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002444386,"threshold_uncertainty_score":0.003087461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008592092080135814,"score_gpt":0.2309869368026069,"score_spread":0.2223948447224711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}