{"id":"W1560285111","doi":"10.1111/j.1751-7915.2010.00185.x","title":"Mining bacterial genomes for novel arylesterase activity","year":2010,"lang":"en","type":"article","venue":"Microbial Biotechnology","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Health and Long Term Care; Ontario Institute for Cancer Research; University of Toronto","funders":"National Institutes of Health; Ontario Genomics; Ontario Genomics Institute; Genome Canada","keywords":"Streptomyces avermitilis; Esterase; Biochemistry; Pseudomonas putida; Enzyme; Arylesterase; Rhodopseudomonas palustris; Escherichia coli; Bacterial genome size; Genome; Gene; Biology; Chemistry; Bacteria; Streptomyces; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001102888,0.0001385189,0.0001481774,0.00007357547,0.00008985792,0.00002399668,0.0002046098,0.0005678595,0.00002625048],"category_scores_gemma":[0.0001118773,0.0001394975,0.00009110511,0.00008086077,0.0001333011,0.000004657082,0.0001205951,0.0001150875,0.000006086608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007256973,"about_ca_system_score_gemma":0.00004514607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006405089,"about_ca_topic_score_gemma":0.0001851164,"domain_scores_codex":[0.999211,0.000009034552,0.0001422471,0.0003792587,0.00002715953,0.0002313537],"domain_scores_gemma":[0.9994526,0.000009719537,0.00008223716,0.0003712524,0.00005151615,0.00003268681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009078495,0.00007930669,0.00006010709,0.000008297064,0.00002550424,2.720155e-7,0.000009510667,0.000001579033,0.9916474,0.000128321,0.0009635467,0.006985366],"study_design_scores_gemma":[0.0005572173,0.0001408886,0.00009283885,0.000001810444,0.00001318172,0.00001949243,0.000008327263,0.00001865625,0.7980525,0.000004777331,0.2009546,0.0001357002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875352,0.0000471157,0.01094898,0.0004835902,0.0005981006,0.0002309082,0.00009141203,0.00003638291,0.00002834021],"genre_scores_gemma":[0.9919882,0.00002816403,0.006622646,0.0001273826,0.0004122921,0.00003047079,0.0005088609,0.0000243872,0.0002576256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1999911,"threshold_uncertainty_score":0.5688543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008592092080135814,"score_gpt":0.2309869368026069,"score_spread":0.2223948447224711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}