{"id":"W1560404575","doi":"10.1161/circ.130.suppl_2.15460","title":"Abstract 15460: Pulmonary Hypertension is Associated with Apoptosis, the Downregulation of S100A1, the Upregulation of S100A6 and the Receptor for Advanced Glycation end-Products","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Rage (emotion); Medicine; TUNEL assay; Pulmonary hypertension; Downregulation and upregulation; Glycation; Apoptosis; Lung; Receptor; Endocrinology; Internal medicine; Andrology; Pathology; Biology; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009508982,0.0003237104,0.0003789967,0.0003212527,0.0001828489,0.0002246589,0.0001198517,0.0003461452,0.01079262],"category_scores_gemma":[0.0002089654,0.0001150303,0.0002057522,0.0001963662,0.000266848,0.0001520546,0.0002382662,0.0004032837,0.001772443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001311024,"about_ca_system_score_gemma":0.00008749349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002131083,"about_ca_topic_score_gemma":0.0001513128,"domain_scores_codex":[0.9998826,0.0000163062,0.0000109165,0.00003584045,0.00003575951,0.00001858813],"domain_scores_gemma":[0.9998683,0.00002674794,0.0000374973,0.000009530018,0.00002239004,0.0000354907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001848512,0.0001863898,0.03316864,0.0004471366,0.00006756136,0.004120934,0.0001467046,0.00004118969,0.9337716,0.0001242659,0.001593598,0.02448353],"study_design_scores_gemma":[0.0002028261,0.002757493,0.7738794,0.00007348089,0.0001283081,0.04649872,0.0002315874,0.0004585894,0.1602639,0.0002220317,0.01526767,0.00001607662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910446,0.00347042,0.001220004,0.0002735511,0.0001230463,0.00003268916,0.0008556938,0.0001029046,0.002876972],"genre_scores_gemma":[0.9907091,0.001015936,0.0005823569,0.0001150658,0.0001152702,0.00004273251,0.001212613,0.00001673222,0.006190165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01079262,"threshold_uncertainty_score":0.03610486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009553657155980874,"score_gpt":0.2085923694665164,"score_spread":0.1990387123105355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}