{"id":"W1560657444","doi":"10.1016/s0065-3233(03)01025-8","title":"From Clone to Crystal: Maximizing the Amount of Protein Samples for Structure Determination","year":2003,"lang":"en","type":"review","venue":"Advances in protein chemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Proteome; Computational biology; Proteomics; Biology; Folding (DSP implementation); Function (biology); Protein folding; Escherichia coli; Biochemistry; Gene; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002961357,0.001566798,0.003304929,0.002152588,0.0007017386,0.002319697,0.003211164,0.002190862,0.003094863],"category_scores_gemma":[0.003752616,0.001419042,0.001019983,0.003273521,0.001252195,0.003807177,0.001542433,0.004103543,0.0063168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00121814,"about_ca_system_score_gemma":0.001407631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001467975,"about_ca_topic_score_gemma":0.003805053,"domain_scores_codex":[0.9985197,0.0002104296,0.0001120065,0.0002884122,0.0007911978,0.00007820916],"domain_scores_gemma":[0.9976227,0.0007961697,0.0002357928,0.000424438,0.0007977327,0.000123122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003065433,0.0001918482,0.0008495828,0.004667074,0.0001159457,0.0003739829,0.000126592,0.0009238132,0.3364048,0.006322146,0.03309854,0.6166191],"study_design_scores_gemma":[0.0001288748,0.0003019296,0.002234397,0.0005390994,0.0002127866,0.003697215,0.0001063729,0.002042313,0.447365,0.00831218,0.53498,0.00007984247],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0263893,0.5883656,0.3538989,0.007932158,0.00248479,0.0006405828,0.003379994,0.005083044,0.01182563],"genre_scores_gemma":[0.03616248,0.5205325,0.4095235,0.004578555,0.0007905537,0.0009566856,0.009602784,0.00130368,0.01654922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003304929,"threshold_uncertainty_score":0.0156613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02180401004193735,"score_gpt":0.3124784990074456,"score_spread":0.2906744889655083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}