{"id":"W1560958935","doi":"10.1111/j.1365-2567.2011.03538.x","title":"Fine epitope mapping within the pathogenic thyroglobulin peptide 2340–2359: minimal epitopes retaining antigenicity across various MHC haplotypes are not necessarily immunogenic","year":2011,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"General Secretariat for Research and Technology","keywords":"Epitope; Biology; Antigenicity; Thyroglobulin; Major histocompatibility complex; Antigen; Peptide; Epitope mapping; Amino acid; Subdominant; Peptide sequence; Molecular biology; Genetics; Antibody; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009842595,0.0002530647,0.0001067413,0.0001088811,0.00008426471,0.000203765,0.0001465284,0.0001538101,0.0005783248],"category_scores_gemma":[0.00009100463,0.00008588567,0.000162154,0.00006744879,0.0001689979,0.0001358269,0.0002017638,0.0003305647,0.0002222292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001241429,"about_ca_system_score_gemma":0.00009448171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002287486,"about_ca_topic_score_gemma":0.0003148417,"domain_scores_codex":[0.9999366,0.00001195683,0.000005103501,0.0000141539,0.00001397819,0.00001821203],"domain_scores_gemma":[0.9999222,0.00001634158,0.00002190306,0.000009612611,0.000007798372,0.00002220146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003350227,0.000003954131,0.0001432687,0.000005829099,0.000001006257,0.00002926303,0.000005160229,0.00001541718,0.9994666,0.00001578091,0.000002021168,0.0002781983],"study_design_scores_gemma":[0.00001650095,0.000940387,0.01419553,0.000008077232,0.00002839268,0.001230884,0.00006663367,0.0007077229,0.9812683,0.00007861458,0.001451197,0.00000776665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987547,0.0001163796,0.0008244485,0.000008544205,0.000002590816,0.000005821254,0.0000290206,0.000006056247,0.0002523633],"genre_scores_gemma":[0.9981689,0.0001115005,0.001271698,0.00001573393,0.00000342928,0.00000487571,0.0001108894,0.00000522231,0.0003077222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005783248,"threshold_uncertainty_score":0.001934648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03060058915959496,"score_gpt":0.2361775685032665,"score_spread":0.2055769793436715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}