{"id":"W1561767136","doi":"10.1111/ahg.12002","title":"Genotype‐Based Association Analysis Using Discordant Pairs: A Penetrance Odds Ratio Approach","year":2013,"lang":"en","type":"article","venue":"Annals of Human Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"McNemar's test; Odds ratio; Statistics; Score test; Penetrance; Likelihood-ratio test; Genetic association; Genotype; Biology; Mathematics; Genetics; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02438083,0.001152039,0.002041348,0.004322804,0.0004755049,0.001464334,0.003126339,0.001341057,0.001886328],"category_scores_gemma":[0.09371419,0.0007250879,0.001397918,0.002349435,0.001493175,0.001931306,0.001966632,0.001557621,0.0004616602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002853356,"about_ca_system_score_gemma":0.0004837568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005160757,"about_ca_topic_score_gemma":0.0004031421,"domain_scores_codex":[0.9717466,0.02275591,0.0008523762,0.002548194,0.00183349,0.0002634703],"domain_scores_gemma":[0.9264807,0.06558651,0.00290011,0.003968284,0.0007525559,0.0003119543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002407555,0.0005908452,0.2557721,0.0009212046,0.004205615,0.007167756,0.001699857,0.1383914,0.009197868,0.1547949,0.002580445,0.4222704],"study_design_scores_gemma":[0.0002899946,0.001182077,0.02637585,0.00009569246,0.0007527276,0.00937961,0.000275341,0.7903568,0.00395554,0.1640032,0.003192562,0.0001406056],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.05790985,0.0003365241,0.9399202,0.0001706573,0.00003015868,0.0001880874,0.0002011857,0.0003068327,0.0009364503],"genre_scores_gemma":[0.6180124,0.0002967475,0.3799817,0.0001277352,0.00006541669,0.0004243858,0.0002978571,0.00007830369,0.0007153648],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.02438083,"threshold_uncertainty_score":0.1289396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05979904525934441,"score_gpt":0.327271996486529,"score_spread":0.2674729512271846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}