{"id":"W1561786195","doi":"10.1023/a:1013125027697","title":"Tumor Physiology and Drug Resistance","year":2001,"lang":"en","type":"review","venue":"Cancer and Metastasis Reviews","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Drug resistance; Medicine; Repopulation; Clinical trial; Multiple drug resistance; Drug; Cancer; Cancer research; Tumor microenvironment; Tumor cells; Pharmacology; Biology; Pathology; Stem cell; Internal medicine; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003119848,0.0004989053,0.001814317,0.00006035699,0.00009436491,0.00004093229,0.0002029584,0.0001406204,0.00005828531],"category_scores_gemma":[0.0001035472,0.000386496,0.0003493989,0.0001570022,0.00014909,0.000003127179,0.0002120798,0.0001772155,0.00001214396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003154786,"about_ca_system_score_gemma":0.0001945949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001902324,"about_ca_topic_score_gemma":0.0002206029,"domain_scores_codex":[0.9980476,0.0001710448,0.0005983565,0.0007954263,0.00006639391,0.0003211529],"domain_scores_gemma":[0.9988005,0.00004657501,0.0004019647,0.0005317457,0.00004320735,0.0001760603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009313142,0.00001303181,0.000002050139,0.009044755,0.0001196315,0.000004242901,0.000007755593,6.958814e-8,0.00004919483,0.00006644092,0.03458301,0.9561005],"study_design_scores_gemma":[0.0001743628,0.00002296469,0.000003340805,0.00237412,0.0008738021,0.00003174728,0.000003114661,9.744797e-8,0.00003770208,0.00003275388,0.9960284,0.0004176219],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005920429,0.9979459,0.00002207055,0.00003846681,0.0002924997,0.0008103999,0.0003025865,0.000006007135,0.000522858],"genre_scores_gemma":[0.00000228042,0.9941791,0.0004445846,0.0004247004,0.0006153184,0.0005710975,0.0002126519,0.00005788516,0.00349233],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9614454,"threshold_uncertainty_score":0.9998587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04043265027334428,"score_gpt":0.3383163589063233,"score_spread":0.2978837086329791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}