{"id":"W1562034521","doi":"10.1186/1471-2407-5-149","title":"Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases","year":2005,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; University of Ottawa; McGill University","funders":"McGill University Health Centre; McGill University","keywords":"Surgical oncology; Medicine; Proprotein Convertases; Colorectal cancer; Internal medicine; Oncology; Cancer research; General surgery; Cancer; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006016091,0.00007804186,0.00008656279,0.00001572982,0.00005790291,0.00001006267,0.00005268465,0.00005495719,0.00002027042],"category_scores_gemma":[0.00001175877,0.00005332642,0.00001959215,0.00003220318,0.00007727511,0.000008966795,0.00009126284,0.00004378808,1.328615e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000074624,"about_ca_system_score_gemma":0.00005900516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001377626,"about_ca_topic_score_gemma":0.0004853658,"domain_scores_codex":[0.999531,0.00003733262,0.0001056024,0.0001582713,0.00006735338,0.0001004064],"domain_scores_gemma":[0.9998102,0.000002678895,0.00005966787,0.00007865017,0.00002309036,0.00002569949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006595864,0.00002621694,0.003161353,0.00007097721,0.000003818856,4.387263e-7,0.00005526553,0.000007050716,0.994093,0.00001765593,0.0001120426,0.00238625],"study_design_scores_gemma":[0.0004446626,0.00008254436,0.003117899,0.0000650226,0.0000136744,0.000004826241,0.00003864077,0.0000741634,0.9948575,0.00001613798,0.001207684,0.00007727549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925538,0.007023728,0.00004384883,0.00002207094,0.00001505682,0.0002673964,0.00002326995,0.000002893345,0.00004788643],"genre_scores_gemma":[0.9991507,0.0001044424,0.0004049831,0.0000691469,0.00008475533,0.0000767611,0.000005360168,0.000007194402,0.00009664683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006919286,"threshold_uncertainty_score":0.2174588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01133043013678965,"score_gpt":0.2504856631507671,"score_spread":0.2391552330139775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}