{"id":"W1562662251","doi":"10.3389/fncel.2015.00185","title":"Expression and contributions of the Kir2.1 inward-rectifier K+ channel to proliferation, migration and chemotaxis of microglia in unstimulated and anti-inflammatory states","year":2015,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"","keywords":"Microglia; Chemotaxis; Inward-rectifier potassium ion channel; Cell biology; Stimulation; Patch clamp; Inflammation; Ion channel; Biology; Chemistry; Neuroscience; Immunology; Electrophysiology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002083754,0.0001966522,0.0002987242,0.0001924281,0.0001892339,0.000369612,0.0001595852,0.0004693137,0.0009155654],"category_scores_gemma":[0.0003286147,0.0001446293,0.0002863379,0.0001680069,0.0002749395,0.0004285938,0.0001542879,0.0005316363,0.0002492354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002991565,"about_ca_system_score_gemma":0.0002868872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006280327,"about_ca_topic_score_gemma":0.0008034613,"domain_scores_codex":[0.9996994,0.0000437273,0.00003432123,0.00005056893,0.00005622187,0.0001157665],"domain_scores_gemma":[0.9998746,0.00002641109,0.00002453407,0.0000097797,0.0000254458,0.00003931433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003972281,0.00002287599,0.0003537785,0.00006378353,0.000003357191,0.00004853394,0.00003808964,0.00002970506,0.9978542,0.00006168889,0.00002280872,0.001104078],"study_design_scores_gemma":[0.00007380507,0.001256475,0.06343052,0.00002697766,0.00005868752,0.0008139151,0.0003517899,0.001340057,0.9289706,0.0002482862,0.003399548,0.00002950144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941368,0.003342272,0.0008812204,0.0001219267,0.00003441193,0.00002022714,0.0002541393,0.00002116887,0.001187838],"genre_scores_gemma":[0.9949089,0.002012082,0.001217215,0.0001244996,0.00003844658,0.00007525781,0.0003394093,0.00001004798,0.001274121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009155654,"threshold_uncertainty_score":0.003062844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01785681821212124,"score_gpt":0.2353141804172618,"score_spread":0.2174573622051406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}