{"id":"W1562977875","doi":"10.1016/s0076-6879(05)05008-1","title":"Analysis of Glycosylphosphatidylinositol Protein Anchors: The Prion Protein","year":2005,"lang":"en","type":"review","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"","keywords":"Neurodegeneration; Prion protein; Proteome; Human proteome project; Membrane protein; Membrane; Biology; Chemistry; Computational biology; Cell biology; Biochemistry; Proteomics; Medicine; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007195577,0.00114702,0.001291501,0.00175094,0.000187558,0.000883382,0.001180136,0.001178719,0.0006629441],"category_scores_gemma":[0.0005798347,0.0003707675,0.0003696065,0.00159914,0.000797352,0.0009991946,0.0004959454,0.001653362,0.001846391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006833207,"about_ca_system_score_gemma":0.0004581613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00067884,"about_ca_topic_score_gemma":0.0006620542,"domain_scores_codex":[0.9997287,0.00002954978,0.00001980224,0.00007536939,0.0001243083,0.00002219117],"domain_scores_gemma":[0.9997353,0.00009179205,0.00004646895,0.000020069,0.00008680392,0.00001963918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001415163,0.0001431294,0.0003838979,0.006211186,0.00007095806,0.0005402162,0.00007288274,0.0009073697,0.1901736,0.005726724,0.007034307,0.7885941],"study_design_scores_gemma":[0.000055359,0.0003122228,0.002372011,0.001034125,0.0001801215,0.004572596,0.0001012532,0.001828982,0.3613102,0.007050821,0.6210934,0.00008880669],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00683412,0.9710124,0.01579748,0.0005144044,0.0004595224,0.00003658966,0.0001548972,0.0001268193,0.005063784],"genre_scores_gemma":[0.02300046,0.9574484,0.0132453,0.0003302329,0.0002159314,0.00004737954,0.0004258908,0.00003099221,0.005255377],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00175094,"threshold_uncertainty_score":0.004957855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05720576541327391,"score_gpt":0.4526336564035467,"score_spread":0.3954278909902729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}