{"id":"W1563482732","doi":"10.1046/j.1471-4159.2001.00448.x","title":"Transfection‐enforced Bcl‐2 overexpression and an anti‐Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde‐3‐phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, <i>N</i>‐methyl(<i>R</i>)salsolinol","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":168,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institutes of Health","keywords":"Glyceraldehyde 3-phosphate dehydrogenase; Apoptosis; Biology; Neurotoxin; Cell biology; Endogeny; Transfection; Dopaminergic; Caspase; Molecular biology; Programmed cell death; Cell culture; Biochemistry; Dopamine; Dehydrogenase; Enzyme; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002569282,0.000287454,0.0003421757,0.00007113305,0.0001250384,0.00004293435,0.0002419029,0.0002385984,0.00002822488],"category_scores_gemma":[0.0000433602,0.000265719,0.0001708499,0.0001319691,0.00004953573,0.00006229617,0.00005082254,0.0002411646,4.003088e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001808421,"about_ca_system_score_gemma":0.00005921012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002122266,"about_ca_topic_score_gemma":0.000002220914,"domain_scores_codex":[0.9981819,0.0001346296,0.0006900181,0.0004016764,0.0003255701,0.0002661684],"domain_scores_gemma":[0.9985432,0.00001822765,0.0005911169,0.0003650646,0.0002087164,0.0002736819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006096481,0.0003922158,0.0002064494,0.00006686065,0.00003726859,0.00002565464,0.00008281144,0.001483111,0.9951838,0.000002623112,0.00007681144,0.001832716],"study_design_scores_gemma":[0.001730332,0.000923856,0.001020828,0.00006148427,0.00007080612,0.0006965021,0.0000485682,0.001940322,0.9901454,0.00003341465,0.003077562,0.000250926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985203,0.0005794458,0.0003707992,0.00003745179,0.0001336411,0.0002428811,0.00001690992,0.00001485546,0.00008368422],"genre_scores_gemma":[0.9969847,0.002107603,0.0002176374,0.0001260578,0.0003223715,0.000003924393,0.00009178219,0.0000560296,0.00008985154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00503843,"threshold_uncertainty_score":0.9999795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02351740245842301,"score_gpt":0.2779719702482416,"score_spread":0.2544545677898186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}